Demeton-s-methyl sulfone
Names
[ CAS No. ]:
17040-19-6
[ Name ]:
Demeton-s-methyl sulfone
[Synonym ]:
S-2-Ethylsulfonylethyl O,O-dimethyl phosphorothioate
Phosphorothioic acid, S-(2-(ethylsulfonyl)ethyl) O,O-dimethyl ester
S-[2-(Ethylsulfonyl)ethyl]-O,O-dimethylthiophosphat
1-dimethoxyphosphorylsulfanyl-2-ethylsulfonylethane
S-[2-(ethanesulfonyl)ethyl] O,O-dimethyl phosphorothioate
Thiophosphate de S-[2-(éthylsulfonyl)éthyle] et de O,O-diméthyle
S-[2-(Ethylsulfonyl)ethyl] O,O-dimethyl phosphorothioate
EINECS 241-109-5
DEMETON-S-METHYL SULPHONE
Demeton-S-methylsulfone
Phosphorothioic acid, S-[2-(ethylsulfonyl)ethyl] O,O-dimethyl ester
MFCD00055415
Demeton-S-methylsulfone
Demeton-s-methyl sulfone
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
393.5±44.0 °C at 760 mmHg
[ Melting Point ]:
52℃
[ Molecular Formula ]:
C6H15O5PS2
[ Molecular Weight ]:
262.284
[ Flash Point ]:
191.8±28.4 °C
[ Exact Mass ]:
262.009857
[ PSA ]:
113.16000
[ LogP ]:
-0.11
[ Appearance of Characters ]:
solid
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.482
[ Water Solubility ]:
Soluble (63 g/L) (25 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TF9050000
- CHEMICAL NAME :
- Phosphorothioic acid, O,O-dimethyl S-(2-(ethylsulfonyl)ethyl) ester
- CAS REGISTRY NUMBER :
- 17040-19-6
- BEILSTEIN REFERENCE NO. :
- 1712536
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 12
- MOLECULAR FORMULA :
- C6-H15-O5-P-S2
- MOLECULAR WEIGHT :
- 262.30
- WISWESSER LINE NOTATION :
- WS2&2SPO&O1&O1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 32400 ug/kg
- TOXIC EFFECTS :
- Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other esterases
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 195 mg/m3/4H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 21 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 22 mg/kg
- TOXIC EFFECTS :
- Behavioral - general anesthetic Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other esterases
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 40 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 30 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 120 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 85 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Escherichia coli
- DOSE/DURATION :
- 5 mg/plate
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 28,405,1975 *** REVIEWS *** TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 63,1,1976
Safety Information
[ Symbol ]:
GHS06, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H300 + H330-H311-H411
[ Precautionary Statements ]:
P260-P264-P273-P280-P284-P301 + P310
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T: Toxic;N: Dangerous for the environment;
[ Risk Phrases ]:
21-25-51/53
[ Safety Phrases ]:
S22;S28;S45;S61;S36/S37
[ RIDADR ]:
UN 2783
[ RTECS ]:
TF9050000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1(a)
[ HS Code ]:
29159000