6-Hydroxy-2-naphthoic acid

Names

[ Name ]:
6-Hydroxy-2-naphthoic acid

[Synonym ]:
MFCD00060070
6-Hydroxy-2-naphthoic acid
2-Naphthol-6-carboxylic Acid
2-Naphthalenecarboxylic acid, 6-hydroxy-
6-hydroxynaphthalene-2-carboxylic acid
EINECS 240-759-7

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
407.0±20.0 °C at 760 mmHg

[ Melting Point ]:
240-250 °C(lit.)

[ Molecular Formula ]:
C₁₁H₈O₃

[ Molecular Weight ]:
188.179

[ Flash Point ]:
214.1±18.3 °C

[ Exact Mass ]:
188.047348

[ PSA ]:
57.53000

[ LogP ]:
2.39

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.716

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S37/39-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
QN3722500

[ HS Code ]:
2918290000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918290000

[ Summary ]:
HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

Articles

Novel Bradykinin Analogues Modified in the N-Terminal Part of the Molecule with a Variety of Acyl Substituents.

Int. J. Pept. Res. Ther. 18(2) , 117-124, (2012)

In the current work we present some pharmacological characteristics of ten new analogues of bradykinin (Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg) modified in the N-terminal part of the molecule with a vari...

Biocatalytic synthesis of dihydroxynaphthoic acids by cytochrome P450 CYP199A2.

Biosci. Biotechnol. Biochem. 73(12) , 2796-9, (2009)

CYP199A2, a bacterial P450 monooxygenase from Rhodopseudomonas palustris, was found to exhibit oxidation activity towards three hydroxynaphthoic acids. Whole cells of the recombinant Escherichia coli ...

Co-crystals of caffeine and hydroxy-2-naphthoic acids: unusual formation of the carboxylic acid dimer in the presence of a heterosynthon.

Mol. Pharm. 4(3) , 339-46, (2007)

A group of caffeine-containing co-crystals of hydroxy-2-naphthoic acids were synthesized and analyzed via single-crystal X-ray diffraction and IR analysis. The imidazole-carboxylic acid synthon was ob...