6-Bromo-2-naphthol
Names
[ CAS No. ]:
15231-91-1
[ Name ]:
6-Bromo-2-naphthol
[Synonym ]:
6-Bromo-β-naphthol
6-Bromo-2-naphthol
6-bromonaphthalen-2-ol
EINECS 239-279-0
2-Naphthalenol, 6-bromo-
MFCD00004081
Chemical & Physical Properties
[ Density]:
1.6±0.1 g/cm3
[ Boiling Point ]:
353.8±15.0 °C at 760 mmHg
[ Melting Point ]:
122-124 °C(lit.)
[ Molecular Formula ]:
C10H7BrO
[ Molecular Weight ]:
223.066
[ Flash Point ]:
167.8±20.4 °C
[ Exact Mass ]:
221.968018
[ PSA ]:
20.23000
[ LogP ]:
3.48
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.705
[ Storage condition ]:
Store at RT.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QL3365000
- CHEMICAL NAME :
- 2-Naphthol, 6-bromo-
- CAS REGISTRY NUMBER :
- 15231-91-1
- LAST UPDATED :
- 199109
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C10-H7-Br-O
- MOLECULAR WEIGHT :
- 223.08
- WISWESSER LINE NOTATION :
- L66J CQ HE
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 325 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 13,381,1978
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
QL3365000
[ HS Code ]:
2908199090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2908199090
[ Summary ]:
HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0%
Articles
Anal. Biochem. 120 , 66, (1982)
α-Glucosidases separated on isoelectric focusing gels can be localized by a two-step staining procedure. First, bromonaphthyl-α- d-glucoside is cleaved by the α-glucosidases in the gel; then, the rele...
A new series of kinked liquid crystals: 2-(6-alkoxynaphthalen-2-yl)-6-methoxyquinolines.Int. J. Mol. Sci. 16 , 7520-34, (2015)
A new series of 2-(6-alkoxynaphthalen-2-yl)-6-methoxyquinolines (nO-NpQOMe, n = 3-8) liquid crystal compounds, a linear molecular structure with two kinks, were synthesized using a short two-step reac...
Visualizing antibody-catalyzed retro-aldol-retro-Michael reactions.Bioorg. Med. Chem. Lett. 11(22) , 2983-6, (2001)
We developed a visible detection system for antibody-catalyzed retro-aldol-retro-Michael reactions. Aldolase antibody 38C2 catalyzed the reaction of substrate 1 to provide 6-bromo-2-napthol that forms...