CB-618 sodium salt
Names
[ CAS No. ]:
1628207-16-8
[ Name ]:
CB-618 sodium salt
[Synonym ]:
1,6-Diazabicyclo[3.2.1]octan-7-one, 2-(1,3,4-oxadiazol-2-yl)-6-(sulfooxy)-, sodium salt, (2S,5R)- (1:1)
Sodium ({[(2S,5R)-2-(1,3,4-oxadiazol-2-yl)-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl]oxy}sulfonyl)oxidanide
Biological Activity
[Description]:
CB-618 (CB 238618) is a novel non-β-lactam β-lactamase inhibitor that potentiates meropenem MIC values against clinical Enterobacteriaceae isolates; displays a minimal antibacterial effect alone, potentiates the meropenem MIC values of 16-512 mg/ml to 0.25-2 mg/ml.
[References]
References 1. VanScoy BD, et al. Antimicrob Agents Chemother. 2016 Jun 20;60(7):3891-6. 2. Ambrose PG, et al. Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e00630-17. View Related Products by Target Bacterial
Chemical & Physical Properties
[ Molecular Formula ]:
C8H10N4O6S.Na
[ Molecular Weight ]:
312.235
[ Exact Mass ]:
312.014038