Clivatuzumab

Names

[ CAS No. ]:
1622075-09-5

[ Name ]:
Clivatuzumab

Biological Activity

[Description]:

Clivatuzumab is a humanized anti-mucin monoclonal antibody targeting an epitope in the MUC1 antigen expressed in most pancreatic cancers[1].

[Related Catalog]:

Research Areas >> Cancer

[In Vitro]

Clivatuzumab 对胰腺导管腺癌 (PDAC) 表现出高特异性，对正常和良性非肿瘤性胰腺组织几乎没有反应性，尽管它对某些其他器官(如胃、结肠、肺)的腺癌表现出有限的反应性(约占所有样本的 10%)[1]。

[References]

[1]. Gold DV, et al. Mapping PAM4 (clivatuzumab), a monoclonal antibody in clinical trials for early detection and therapy of pancreatic ductal adenocarcinoma, to MUC5AC mucin. Mol Cancer. 2013 Nov 20;12(1):143.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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