N-Acetylhexosamine kinase

Names

[ CAS No. ]:
1609980-80-4

[ Name ]:
N-Acetylhexosamine kinase

Biological Activity

[Description]:

N-Acetylhexosamine kinase (NahK) is an anomeric kinase acting on a glucose-type substrate. N-Acetylhexosamine kinase catalyzes the phosphorylation of GlcNAc or GalNAc at the anomeric C1 position with ATP to form N-acetylhexosamine 1-phosphate (GlcNAc-1P/GalNAc-1P)[1][2].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Sato M, et al. Open-close structural change upon ligand binding and two magnesium ions required for the catalysis of N-acetylhexosamine 1-kinase. Biochim Biophys Acta. 2015 May;1854(5):333-40.  

[2]. Wang KC, et al. Insights into the binding specificity and catalytic mechanism of N-acetylhexosamine 1-phosphate kinases through multiple reaction complexes. Acta Crystallogr D Biol Crystallogr. 2014 May;70(Pt 5):1401-10.  

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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