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LY 222306

Names

[ CAS No. ]:
154446-98-7

[ Name ]:
LY 222306

Biological Activity

[Description]:

LY 222306 is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor with a Ki of 0.77 nM.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Cancer

[Target]

Ki: 0.77 nM (GARFT)[1]


[References]

[1]. Habeck LL, et al. A novel class of monoglutamated antifolates exhibits tight-binding inhibition of human glycinamide ribonucleotide formyltransferase and potent activity against solid tumors. Cancer Res. 1994 Feb 15;54(4):1021-6.


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Molecular Formula ]:
C19H23N5O7

[ Molecular Weight ]:
433.42

Related Compounds

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