Cyclo(Phe-Val)

Names

[ Name ]:
Cyclo(Phe-Val)

[Synonym ]:
2,5-Piperazinedione,3-benzyl-6-isopropyl
Valyl-phenylalanyl-anhydrid
3-Benzyl-6-isopropyl-piperazin-2,5-dion
3-benzyl-6-isopropyl-piperazine-2,5-dione
c-L-Val-D-Phe
3-Benzyl-6-isopropyl-2,5-piperazinedione
3-Benzyl-6-isopropyl-2,5-dioxo-piperazin

Biological Activity

[Description]:

Antibacterial agent 134 (compound 1) is an diketopiperazine alkaloid with antimicrobial activity. Antibacterial agent 134 is the major metabolite in the culture of Hymeniacidon perleve associated bioactive bacterium Pseudomonas sp. NJ6-3-1[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Zheng L, et al. Hymeniacidon perleve associated bioactive bacterium pseudomonas sp. NJ6-3-1. Prikl Biokhim Mikrobiol. 2005 Jan-Feb;41(1):35-9.

Chemical & Physical Properties

[ Density]:
1.109g/cm3

[ Boiling Point ]:
515.6ºC at 760mmHg

[ Molecular Formula ]:
C₁₄H₁₈N₂O₂

[ Molecular Weight ]:
246.30500

[ Flash Point ]:
210.4ºC

[ Exact Mass ]:
246.13700

[ PSA ]:
65.18000

[ LogP ]:
1.42010

[ Vapour Pressure ]:
9.73E-11mmHg at 25°C

[ Index of Refraction ]:
1.528

Safety Information

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%