Antibiotic 1142
Names
[ CAS No. ]:
1438-30-8
[ Name ]:
Antibiotic 1142
[Synonym ]:
4-{4-[(N-carbamimidoyl-glycyl)-amino]-1-methyl-pyrrole-2-carbonylamino}-1-methyl-pyrrole-2-carboxylic acid-(2-carbamimidoyl-ethylamide)
t1384
Netropsin dihydrochloride
ia887
4-{4-[(N-Carbamimidoyl-glycyl)-amino]-1-methyl-pyrrol-2-carbonylamino}-1-methyl-pyrrol-2-carbonsaeure-(2-carbamimidoyl-aethylamid)
ch-777-a
Congocidin Sinanomycin
congocidin
ultrapuregrade
2814-a
antibiotic1142
Chemical & Physical Properties
[ Density]:
1.52g/cm3
[ Boiling Point ]:
544.74°C (rough estimate)
[ Melting Point ]:
171-173℃
[ Molecular Formula ]:
C18H26N10O3
[ Molecular Weight ]:
430.46400
[ Exact Mass ]:
430.21900
[ PSA ]:
208.93000
[ LogP ]:
1.62120
[ Appearance of Characters ]:
powder | faint yellow
[ Vapour Pressure ]:
1.75E-23mmHg at 25°C
[ Index of Refraction ]:
1.6500 (estimate)
[ Storage condition ]:
−20°C
[ Water Solubility ]:
H2O: 1 mg/mL
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DW2973000
- CHEMICAL NAME :
- N,4'-Bi(pyrrole-2-carboxamide), N'-(2-carbamoylethyl)-4-((2-guanidinoacetimidoyl)amin o)-1,1'- dimethyl-
- CAS REGISTRY NUMBER :
- 1438-30-8
- BEILSTEIN REFERENCE NO. :
- 0376913
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C18-H26-N10-O3
- MOLECULAR WEIGHT :
- 430.54
- WISWESSER LINE NOTATION :
- T5NJ A1 BVM2VZ EMV- BT5NJ A1 DMYUM&1MYZUM
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 70 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 17 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 500 umol/L
- REFERENCE :
- MLBRBU Molecular Biology Reports. (Dr. W. Junk Pub., POB 163, 3300 AD Dordrect, Netherlands) V.1- 1973- Volume(issue)/page/year: 2,135,1975
Safety Information
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
R22
[ Safety Phrases ]:
S36
[ RIDADR ]:
UN 2811 6.1/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
DW2973000