10H-Phenothiazine-10-propanamine,N,N,b-trimethyl-2-(methylthio)-,hydrochloride (1:1)
Names
[ CAS No. ]:
14056-64-5
[ Name ]:
10H-Phenothiazine-10-propanamine,N,N,b-trimethyl-2-(methylthio)-,hydrochloride (1:1)
[Synonym ]:
Promethazine sulfoxide
10-(2-dimethyl-aminopropyl)-phenothiazine sulphoxide
dimethyl-[2-methyl-3-(2-methylsulfanyl-phenothiazin-10-yl)-propyl]-amine,monohydrochloride
Methiomeprazin*HCl
Romergan sulfoxide
Promethazine 5-Oxide
10-(2-(Dimethylamino)propyl)-10H-phenothiazine 5-oxide
Promethiazine sulfoxide
Promethazine 5-Sulfoxide
promethasine sulfoxide
methiomeprazine,monohydrochloride
Chemical & Physical Properties
[ Boiling Point ]:
480.8ºC at 760 mmHg
[ Molecular Formula ]:
C19H25ClN2S2
[ Molecular Weight ]:
380.99800
[ Flash Point ]:
244.6ºC
[ Exact Mass ]:
380.11500
[ PSA ]:
57.08000
[ LogP ]:
6.07590
[ Vapour Pressure ]:
2.1E-09mmHg at 25°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SO6300000
- CHEMICAL NAME :
- Phenothiazine, 10-(3-(dimethylamino)-2-methylpropyl)-2-(methylthio)- , hydrochloride
- CAS REGISTRY NUMBER :
- 14056-64-5
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C19-H24-N2-S2.Cl-H
- MOLECULAR WEIGHT :
- 381.03
- WISWESSER LINE NOTATION :
- T C666 BN ISJ B1Y1&1N1&1 ES1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 145 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,30,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 700 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,30,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 80 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,30,1972