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14056-64-5

14056-64-5 structure
14056-64-5 structure

Name N,N,2-trimethyl-3-(2-methylsulfanylphenothiazin-10-yl)propan-1-amine,hydrochloride
Synonyms Promethazine sulfoxide
10-(2-dimethyl-aminopropyl)-phenothiazine sulphoxide
dimethyl-[2-methyl-3-(2-methylsulfanyl-phenothiazin-10-yl)-propyl]-amine,monohydrochloride
Methiomeprazin*HCl
Romergan sulfoxide
Promethazine 5-Oxide
10-(2-(Dimethylamino)propyl)-10H-phenothiazine 5-oxide
Promethiazine sulfoxide
Promethazine 5-Sulfoxide
promethasine sulfoxide
methiomeprazine,monohydrochloride
Boiling Point 480.8ºC at 760 mmHg
Molecular Formula C19H25ClN2S2
Molecular Weight 380.99800
Flash Point 244.6ºC
Exact Mass 380.11500
PSA 57.08000
LogP 6.07590
Vapour Pressure 2.1E-09mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SO6300000
CHEMICAL NAME :
Phenothiazine, 10-(3-(dimethylamino)-2-methylpropyl)-2-(methylthio)- , hydrochloride
CAS REGISTRY NUMBER :
14056-64-5
LAST UPDATED :
199012
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C19-H24-N2-S2.Cl-H
MOLECULAR WEIGHT :
381.03
WISWESSER LINE NOTATION :
T C666 BN ISJ B1Y1&1N1&1 ES1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
145 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,30,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,30,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
80 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,30,1972