Hydroxy-PEG3-MS
Names
[ CAS No. ]:
139115-89-2
[ Name ]:
Hydroxy-PEG3-MS
[Synonym ]:
2-(2-(2-hydroxyethoxy)ethoxy)ethyl methanesulfonate
8-hydroxy-3,6-dioxaoctyl methanesulphonate
triethylene glycol
Hydroxy-PEG3-MS
Biological Activity
[Description]:
Hydroxy-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[Related Catalog]:
[Target]
PEGs
[In Vitro]
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C7H16O6S
[ Molecular Weight ]:
228.26300
[ Exact Mass ]:
228.06700
[ PSA ]:
90.44000
[ LogP ]:
0.06890