Teneligliptin D8

Names

[ CAS No. ]:
1391012-95-5

[ Name ]:
Teneligliptin D8

[Synonym ]:
Methanone, [(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl-2,2,3,3,5,5,6,6-d8]-2-pyrrolidinyl]-3-thiazolidinyl-
{(2S,4S)-4-[4-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)(2H8)-1-piperazinyl]-2-pyrrolidinyl}(1,3-thiazolidin-3-yl)methanone

Biological Activity

[Description]:

Teneligliptin D8 (MP-513 D8) a deuterium labeled Teneligliptin (MP-513). Teneligliptin is a potent, orally available, competitive, and long-lasting DPP-4 inhibitor[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Metabolic Enzyme/Protease >> Dipeptidyl Peptidase

[References]

[1]. Fukuda-Tsuru S, et al. A novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor, teneligliptin, improves postprandial hyperglycemia and dyslipidemia after single and repeated administrations. Eur J Pharmacol. 2012 Dec 5;696(1-3):194-202.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
663.4±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C22H22D8N6OS

[ Molecular Weight ]:
434.628

[ Flash Point ]:
355.0±31.5 °C

[ Exact Mass ]:
434.270386

[ LogP ]:
1.15

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.721

Related Compounds