Bromo-PEG2-C2-Boc

Names

[ CAS No. ]:
1381861-91-1

[ Name ]:
Bromo-PEG2-C2-Boc

[Synonym ]:
Bromo-PEG3-t-butyl ester

Biological Activity

[Description]:

Bromo-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

Alkyl/ether

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

[ Density]:
1.240±0.06 g/cm3

[ Boiling Point ]:
332.0±22.0 °C

[ Molecular Formula ]:
C₁₁H₂₁BrO₄

[ Molecular Weight ]:
297.18604

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.