GPVI antagonist 1

Names

[ CAS No. ]:
1327156-14-8

[ Name ]:
GPVI antagonist 1

Biological Activity

[Description]:

GPVI antagonist 1 (compound 5) is a glycoprotein VI (GPVI) platelet receptor antagonist. GPVI antagonist 1 inhibits collagen-induced platelet aggregation with an IC50 of 25.3 μM[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Others >> Others

[References]

[1]. Holly Foster, et al. A Comparative Assessment Study of Known Small-molecule GPVI Modulators. ACS Med Chem Lett. 2022 Jan 20;13(2):171-181.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H19N3O4S

[ Molecular Weight ]:
385.44

Related Compounds