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Decarboxy Moxifloxacin

Names

[ CAS No. ]:
1322062-57-6

[ Name ]:
Decarboxy Moxifloxacin

[Synonym ]:
4(1H)-Quinolinone, 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-
1-Cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4(1H)-quinolinone

Biological Activity

[Description]:

Decarboxy Moxifloxacin (compound 8) is a decarboxylated compound of Moxifloxacin. Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Marks KR, et al. Synthesis and evaluation of 1-cyclopropyl-2-thioalkyl-8-methoxy fluoroquinolones.Bioorg Med Chem Lett. 2011 Aug 1;21(15):4585-8.

[2]. Culley, C.M., et al., Moxifloxacin: clinical efficacy and safety. Am J Health Syst Pharm, 2001. 58(5): p. 379-88.

Chemical & Physical Properties

[ Density]:
1.300±0.06 g/cm3 at 20 °C, 760 Torr

[ Boiling Point ]:
561.3±50.0 °C at 760 Torr

[ Molecular Formula ]:
C20H24FN3O2

[ Molecular Weight ]:
357.42

[ Flash Point ]:
293.3±30.1 °C

[ LogP ]:
1.603±0.625 at 25 °C

[ Vapour Pressure ]:
1.25E-12 Torr at 25 °C

[ Storage condition ]:
2-8°C

Safety Information

[ Hazard Codes ]:
N


Related Compounds

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