1-Decarboxy-3-oxo-ceathic acid

Names

[ Name ]:
1-Decarboxy-3-oxo-ceathic acid

[Synonym ]:
Dicyclopenta[a,i]phenanthrene-3a(1H)-carboxylic acid, octadecahydro-5a,5b,8,8,10a-pentamethyl-1-(1-methylethenyl)-9-oxo-, (1R,3aS,5aR,5bR,7aR,10aR,10bR,12aR,12bR)-
(1R,3aS,5aR,5bR,7aR,10aR,10bR,12aR,12bR)-1-Isopropenyl-5a,5b,8,8,10a-pentamethyl-9-oxooctadecahydrodicyclopenta[a,i]phenanthrene-3a(1H)-carboxylic acid

Biological Activity

[Description]:

1-Decarboxy-3-oxo-ceanothic acid is an anticancer agent. 1-Decarboxy-3-oxo-ceanothic acid inhibits DNA synthesis. 1-Decarboxy-3-oxo-ceanothic acid induces Apoptosis[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis

[References]

[1]. Su Y, et al. In vitro cytotoxic activity of 1-decarboxy-3-oxo-ceanothic acid in a human ovarian adenocarcinoma cell line. Res Commun Mol Pathol Pharmacol. 1998 Jun;100(3):313-26.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
535.4±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₉H₄₄O₃

[ Molecular Weight ]:
440.66

[ Flash Point ]:
291.7±26.6 °C

[ Exact Mass ]:
440.329041

[ PSA ]:
54.37000

[ LogP ]:
7.80

[ Vapour Pressure ]:
0.0±3.1 mmHg at 25°C

[ Index of Refraction ]:
1.531

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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