<Suppliers Price>

(+)-Igmesine hydrochloride

Names

[ CAS No. ]:
130152-35-1

[ Name ]:
(+)-Igmesine hydrochloride

[Synonym ]:
Cinnamyl-1-phenyl-1-N-methyl-N-cyclopropylene
JO-1784
Igmesine hydrochloride
Sipatrigine
CI-1019

Biological Activity

[Description]:

(+)-Igmesine hydrochloride (JO1784) is an orally active and selective σ receptor ligand with neuroprotective and anti-amnesic activities[1].

[Related Catalog]:

Research Areas >> Neurological Disease
Signaling Pathways >> GPCR/G Protein >> Sigma Receptor

[References]

[1]. O'Neill M, et al. The sigma receptor ligand JO 1784 (igmesine hydrochloride) is neuroprotective in the gerbil model of global cerebral ischaemia. Eur J Pharmacol. 1995 Sep 5;283(1-3):217-25.  

Chemical & Physical Properties

[ Density]:
1.027g/cm3

[ Boiling Point ]:
445.1ºC at 760mmHg

[ Molecular Formula ]:
C23H30ClN

[ Molecular Weight ]:
355.94

[ Flash Point ]:
196.9ºC

[ Exact Mass ]:
355.20700

[ PSA ]:
3.24000

[ LogP ]:
6.53920

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.