gancaonin L

Names

[ CAS No. ]:
129145-50-2

[ Name ]:
gancaonin L

[Synonym ]:
3-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-8-(3-methyl-but-2-enyl)-chromen-4-one

Biological Activity

[Description]:

Gancaonin L is an isoflavone, that can be isolated from Glycyrrhiza glabra roots. Gancaonin L exhibits significant PPAR-γ ligand-binding activity. Gancaonin L can be used for anti-diabetes and anti-obesity research[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR
Research Areas >> Metabolic Disease

[Target]

PPAR-γ


[References]

[1]. Kuroda M, et al. Phenolics from Glycyrrhiza glabra roots and their PPAR-gamma ligand-binding activity. Bioorg Med Chem. 2010 Jan 15;18(2):962-70.  

Chemical & Physical Properties

[ Molecular Formula ]:
C20H18O6

[ Molecular Weight ]:
354.35

[ Exact Mass ]:
354.11000

[ PSA ]:
111.13000

[ LogP ]:
3.79110

Related Compounds