AQ-RA 741

Names

[ Name ]:
AQ-RA 741

[Synonym ]:
AQ-RA 741
Compstatin control peptide
AQ-RA-741BS

Biological Activity

[Description]:

AQ-RA 741 is a potent and selective M 2 antagonist. AQ-RA 741 inhibits the vagally or agonist-induced bradycardia in rats, cats and guinea-pigs. AQ-RA 741 is used in bradycardiac disorders research[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> mAChR

Research Areas >> Cardiovascular Disease

Signaling Pathways >> GPCR/G Protein >> mAChR

[References]

[1]. Doods H, et al.Cardioselectivityof AQ-RA 741, a novel tricyclic antimuscarinic drug. Eur J Pharmacol. 1991 Jan3;192(1):147-52.

Chemical & Physical Properties

[ Density]:
1.132g/cm3

[ Boiling Point ]:
602.7ºC at 760mmHg

[ Molecular Formula ]:
C₂₇H₃₇N₅O₂

[ Molecular Weight ]:
463.61

[ Flash Point ]:
318.3ºC

[ Exact Mass ]:
463.29500

[ PSA ]:
74.23000

[ LogP ]:
4.24220

[ Vapour Pressure ]:
1.76E-14mmHg at 25°C

[ Index of Refraction ]:
1.566

Safety Information

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%