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hDDAH-1-IN-1

Names

[ CAS No. ]:
1229238-69-0

[ Name ]:
hDDAH-1-IN-1

Biological Activity

[Description]:

hDDAH-1-IN-1 (compound 8a) is a potent and selective non-amino acid catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1), with a Ki of 18 µM[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[Target]

Ki: 18 µM (hDDAH-1)[1]


[References]

[1]. Lunk I, et al. Discovery of N-(4-Aminobutyl)-N'-(2-methoxyethyl)guanidine as the First Selective, Nonamino Acid, Catalytic Site Inhibitor of Human Dimethylarginine Dimethylaminohydrolase-1 (hDDAH-1). J Med Chem. 2019 Dec 31.

Chemical & Physical Properties

[ Molecular Formula ]:
C8H20N4O

[ Molecular Weight ]:
188.27

Related Compounds