AZ 4800
Names
[ CAS No. ]:
1226886-78-7
[ Name ]:
AZ 4800
Biological Activity
[Description]:
AZ 4800 is a potent γ-secretase modulator that reduces Aβ40 and Aβ42 levels in HEK/APPswe cells with IC50 of 26 nM and 60 nM, also decreases Aβ39, whereas increases both Aβ37 and Aβ38.
[References]
References 1. Borgegard T, et al. J Biol Chem. 2012 Apr 6;287(15):11810-9. 2. Strömberg K, et al. FEBS J. 2015 Jan;282(1):65-73. View Related Products by Target γ-secretase
Chemical & Physical Properties
[ Molecular Formula ]:
C24H29N5O3
[ Molecular Weight ]:
435.528