PS 423

Names

[ CAS No. ]:
1221964-37-9

[ Name ]:
PS 423

Biological Activity

[Description]:

PS 423 is a substrate-selective inhibitor of PDK1, inhibits the phosphorylation and activation of S6K without affecting the PKB/Akt signaling pathway in HEK293 cells, the prodrug of PS210; inhibits glucose uptake in C2C12 myoblasts; inhibits S6K but not PKB/Akt downstream signaling in muscle cells.

[References]

References 1. Busschots K, et al. Chem Biol. 2012 Sep 21;19(9):1152-63. 2. Arkin MR, et al. Chem Biol. 2014 Sep 18;21(9):1102-14. View Related Products by Target PDK1

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₂₃F₃O₉

[ Molecular Weight ]:
524.445

PS 423

Names

Biological Activity

Chemical & Physical Properties

Related Compounds