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Vatiquinone

Names

[ CAS No. ]:
1213269-98-7

[ Name ]:
Vatiquinone

[Synonym ]:
Vatiquinone
2-[(3R,6E,10E)-3-hydroxy-3,7,11,15-tetramethylhexadeca-6,10,14-trien-1-yl]-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione
2-[(3R,6E,10E)-3-Hydroxy-3,7,11,15-tetramethyl-6,10,14-hexadecatrien-1-yl]-3,5,6-trimethyl-1,4-benzoquinone
2,5-Cyclohexadiene-1,4-dione, 2-[(3R,6E,10E)-3-hydroxy-3,7,11,15-tetramethyl-6,10,14-hexadecatrien-1-yl]-3,5,6-trimethyl-
UNII-6O85FK9I0X
EPI-743
Vatiquinone (USAN)

Biological Activity

[Description]:

Vatiquinone is a potent cellular oxidative stress protectant, which could be used to treat mitochondrial diseases.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Mitochondrial Metabolism
Research Areas >> Others

[Target]

Mitochondria[1].


[References]

[1]. Kouga T, et al. Japanese Leigh syndrome case treated with EPI-743. Brain Dev. 2018 Feb;40(2):145-149. Brain Dev. 2018 Feb;40(2):145-149.


[Related Small Molecules]

Rotenone | FCCP | Elamipretide | NIM811 | Daidzin | TRO 19622 | Imeglimin hydrochloride | α-Lipoic Acid | Mitochonic acid 5 | ER-000444793 | Mito-TEMPO | lipoic acid | Adjudin | Thiabendazole | Asp-AMS

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
565.6±39.0 °C at 760 mmHg

[ Molecular Formula ]:
C29H44O3

[ Molecular Weight ]:
440.658

[ Flash Point ]:
309.9±23.6 °C

[ Exact Mass ]:
440.329041

[ PSA ]:
54.37000

[ LogP ]:
9.35

[ Vapour Pressure ]:
0.0±3.5 mmHg at 25°C

[ Index of Refraction ]:
1.512

Related Compounds