Ortho-Hydroxyacetophenone
Names
[ CAS No. ]:
118-93-4
[ Name ]:
Ortho-Hydroxyacetophenone
[Synonym ]:
1-(2-Hydroxyphenyl)ethan-1-one
Acetophenone, 2'-hydroxy-
2-Acetylphenol
1-Acetyl-2-hydroxybenzene
Ethanone, 1-(2-hydroxyphenyl)-
MFCD00002219
2’-Hydroxyacetophenone
2-Acetophenol
o-Acetylphenol
2‘-Hydroxyacetophenone
o-Hydroxyacetophenone
QR BV1
Ethanone,1-(2-hydroxyphenyl)-
1-(2-Hydroxyphenyl)ethanone
2-Hydroxyphenyl Methyl Ketone
EINECS 204-288-0
Biological Activity
[Description]:
[Related Catalog]:
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
218.4±13.0 °C at 760 mmHg
[ Melting Point ]:
41735ºC
[ Molecular Formula ]:
C8H8O2
[ Molecular Weight ]:
136.148
[ Flash Point ]:
87.5±12.4 °C
[ Exact Mass ]:
136.052429
[ PSA ]:
37.30000
[ LogP ]:
1.96
[ Vapour density ]:
4.7 (vs air)
[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.552
[ Water Solubility ]:
slightly soluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AM8575000
- CHEMICAL NAME :
- Acetophenone, o-hydroxy-
- CAS REGISTRY NUMBER :
- 118-93-4
- BEILSTEIN REFERENCE NO. :
- 0386123
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C8-H8-O2
- MOLECULAR WEIGHT :
- 136.16
- WISWESSER LINE NOTATION :
- QR BV1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xi:Irritant
[ Risk Phrases ]:
R36/38
[ Safety Phrases ]:
S26-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
AM8575000
[ HS Code ]:
2914509090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2914501900
[ Summary ]:
2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
Articles
Bioresour. Technol. 102(2) , 483-9, (2011)
An (S)-specific carbonyl reductase (SCRII) was purified to homogeneity from Candida parapsilosis by following an anti-Prelog reducing activity of 2-hydroxyacetophenone. Peptide mass fingerprinting ana...
Accessibility and selective stabilization of the principal spin states of iron by pyridyl versus phenolic ketimines: modulation of the 6A1 ↔ 2T2 ground-state transformation of the [FeN4O2]+ chromophore.Inorg. Chem. 51(15) , 8241-53, (2012)
Several potentially tridentate pyridyl and phenolic Schiff bases (apRen and HhapRen, respectively) were derived from the condensation reactions of 2-acetylpyridine (ap) and 2'-hydroxyacetophenone (Hha...
Synthesis, spectral and antimicrobial activity of Zn(II) complexes with Schiff bases derived from 2-hydrazino-5-[substituted phenyl]-1,3,4-thiadiazole and benzaldehyde/2-hydroxyacetophenone/indoline-2,3-dione.Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 113 , 393-9, (2013)
Zn(II) complexes have been synthesized by reacting zinc acetate with Schiff bases derived from 2-hydrazino-5-[substituted phenyl]-1,3,4-thiadiazole and 2-hydroxyacetophenone/benzaldehyde/indoline-2,3-...