19-Hete

Names

[ Name ]:
19-Hete

[Synonym ]:
(5Z,8Z,11Z,14Z,19R)-19-Hydroxy-5,8,11,14-icosatetraenoic acid
19-Hete
5,8,11,14-Eicosatetraenoic acid, 19-hydroxy-, (5Z,8Z,11Z,14Z,19R)-
19r-hydroxy-5z,8z,11z,14z-eicosatetraenoic acid
5,8,11,14-Eicosatetraenoic acid, 19-hydroxy-, (all-Z)-
5,8,11,14-Eicosatetraenoic acid, 19-hydroxy-, (5Z,8Z,11Z,14Z)-
(5Z,8Z,11Z,14Z)-19-Hydroxy-5,8,11,14-icosatetraenoic acid

Biological Activity

[Description]:

19(R)-HETE is a vasodilator in renal arteries, whereas 19(S)-HETE was relatively inactive[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

[In Vitro]

19(R)-HETE (1 μM) increases the diameter of lumen of renal arteries by 15±4 μm from a basal diameter of 233±20 μm[1]. 19(R)-HETE (1 μM) increases vessel diameter by 53±7 μm in vessels preconstricted with 0.1 μM Norepinephrine (HY-13715)[1].

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
477.3±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₃₂O₃

[ Molecular Weight ]:
320.466

[ Flash Point ]:
256.6±25.2 °C

[ Exact Mass ]:
320.235138

[ PSA ]:
57.53000

[ LogP ]:
4.79

[ Vapour Pressure ]:
0.0±2.7 mmHg at 25°C

[ Index of Refraction ]:
1.514

Related Compounds

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