Columbianetin

Names

[ Name ]:
Columbianetin

[Synonym ]:
Columbianetin
Tetrahydro-oroselol
CPD-9799
8-(2-hydroxypropan-2-yl)-8,9-dihydrofuro[2,3-h]chromen-2-one

Biological Activity

[Description]:

Columbianetin is a phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage. Columbianetin exhibits excellent anti-fungal and anti-inflammatory activity[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

[References]

[1]. UziAfek, et al. Columbianetin, a phytoalexin associated with celery resistance to pathogens during storage. 1995. Volume 39, Issue 6, August 1995, Pages 1347-1350.

[2]. Jeong HJ, et al. Anti-inflammatory effect of Columbianetin on activated human mast cells. Biol Pharm Bull. 2009 Jun;32(6):1027-31.

Chemical & Physical Properties

[ Density]:
1.334g/cm3

[ Boiling Point ]:
443ºC at 760 mmHg

[ Molecular Formula ]:
C₁₄H₁₄O₄

[ Molecular Weight ]:
246.25900

[ Flash Point ]:
171.9ºC

[ Exact Mass ]:
246.08900

[ PSA ]:
59.67000

[ LogP ]:
1.86740

[ Vapour Pressure ]:
1.25E-08mmHg at 25°C

[ Index of Refraction ]:
1.61

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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