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GRPP (human) trifluoroacetate salt

Names

[ CAS No. ]:
1132745-52-8

[ Name ]:
GRPP (human) trifluoroacetate salt

[Synonym ]:
L-Aspartic acid, L-arginyl-L-seryl-L-leucyl-L-glutaminyl-L-α-aspartyl-L-threonyl-L-α-glutamyl-L-α-glutamyl-L-lysyl-L-seryl-L-arginyl-L-seryl-L-phenylalanyl-L-seryl-L-alanyl-L-seryl-L-gluta&#xD; minyl-L-alanyl-L-α-aspartyl-L-prolyl-L-leucyl-L-seryl-L-α-aspartyl-L-prolyl-L-α-aspartyl-L-glutaminyl-L-methionyl-L-asparaginyl-L-α-glutamyl-
L-Arginyl-L-seryl-L-leucyl-L-glutaminyl-L-α-aspartyl-L-threonyl-L-α-glutamyl-L-α-glutamyl-L-lysyl-L-seryl-L-arginyl-L-seryl-L-phenylalanyl-L-seryl-L-alanyl-L-seryl-L-glutaminyl-L-alanyl-L-&#xD; α-aspartyl-L-prolyl-L-leucyl-L-seryl-L-α-aspartyl-L-prolyl-L-α-aspartyl-L-glutaminyl-L-methionyl-L-asparaginyl-L-α-glutamyl-L-aspartic acid

Biological Activity

[Description]:

GRPP (human) is a 30 amino acid Gcg-derived peptide. GRPP (human) causes slight increases in plasma insulin and decreases in plasma glucagon. GRPP (human) does not affect insulin secretion in rat islets[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Lynda Whiting, et al. Glicentin-related pancreatic polypeptide inhibits glucose-stimulated insulin secretion from the isolated pancreas of adult male rats. Physiol Rep. 2015 Dec;3(12):e12638.  

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Molecular Formula ]:
C136H215N41O58S

[ Molecular Weight ]:
3384.467

[ Exact Mass ]:
3382.485596

[ LogP ]:
-10.16

[ Index of Refraction ]:
1.685

Related Compounds