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CL2-MMT-SN38

Names

[ CAS No. ]:
1084888-82-3

[ Name ]:
CL2-MMT-SN38

Biological Activity

[Description]:

CL2-MMT-SN38 is a SN-38 derivative. SN-38, an anticancer agent, is an active metabolite of the Topoisomerase I inhibitor Irinotecan (CPT-11)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase

[References]

[1]. Moon SJ, et al. Antibody conjugates of 7-ethyl-10-hydroxycamptothecin (SN-38) for targeted cancer chemotherapy. J Med Chem. 2008;51(21):6916-6926.

Chemical & Physical Properties

[ Molecular Formula ]:
C102H122N12O24

[ Molecular Weight ]:
1900.13

Related Compounds