AL 8697

Names

[ CAS No. ]:
1057394-06-5

[ Name ]:
AL 8697

[Synonym ]:
al 8697

Biological Activity

[Description]:

AL 8697 is a selective p38 MAPK inhibitor with IC50s of 6 nM and 82 nM for p38α and p38β, respectively[1].

[Related Catalog]:

Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK

Research Areas >> Inflammation/Immunology

[Target]

p38α:6 nM (IC50)

p38β:82 nM ()

[References]

[1]. Balagué C, et al. Profiling of dihydroorotate dehydrogenase, p38 and JAK inhibitors in the rat adjuvant-induced arthritis model: a translational study. Br J Pharmacol. 2012 Jun;166(4):1320-32.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₁F₃N₄O

[ Molecular Weight ]:
402.41

[ Exact Mass ]:
402.16700

[ PSA ]:
59.29000

[ LogP ]:
4.70260

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.