m-PEG6-azide

Names

[ CAS No. ]:
1043884-49-6

[ Name ]:
m-PEG6-azide

[Synonym ]:
HexaGME-N3
methoxy-hexa-(ethylene glycol)-azide

Biological Activity

[Description]:

m-PEG6-azide is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

Research Areas >> Inflammation/Immunology

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Gauzy, Laurence, et al. Cytotoxic agents comprising new tomaymycin derivatives and their therapeutic use. Patent WO2007085930A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₃H₂₇N₃O₆

[ Molecular Weight ]:
321.37000

[ Exact Mass ]:
321.19000

[ PSA ]:
105.13000

[ LogP ]:
0.47886

Precursor & DownStream

Precursor

DownStream

Related Compounds

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