ALDH3A1-IN-1

Names

[ CAS No. ]:
1039855-56-5

[ Name ]:
ALDH3A1-IN-1

Biological Activity

[Description]:

ALDH3A1-IN-1 (Compound 18) is a potent inhibitor of ALDH3A1 with an IC50 of 1.61 μM. ALDH3A1-IN-1 is more potent than DEAB against patient-derived primary prostate tumor epithelial cells, as single agents or in combination treatment with docetaxel[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Aldehyde Dehydrogenase (ALDH)
Research Areas >> Cancer

[References]

[1]. Ibrahim AIM, et al. Expansion of the 4-(Diethylamino)benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer. J Med Chem. 2022 Mar 10;65(5):3833-3848.

Chemical & Physical Properties

[ Molecular Formula ]:
C13H18N2O3

[ Molecular Weight ]:
250.29

Related Compounds