Guanosine, 3'-O-methyl-

Names

[ Name ]:
Guanosine, 3'-O-methyl-

[Synonym ]:
2-amino-9-[3-hydroxy-5-(hydroxymethyl)-4-methoxyoxolan-2-yl]-3H-purin-6-one
3'-O-methyl-guanosine
3'-O-Methylguanosin
3'-OMe-G
O3'-methyl-guanosine

Biological Activity

[Description]:

3'-O-Methylguanosine is a methylated nucleoside analogs and a RNA chain terminator. 3'-O-methylguanosine can inhibit early virus-specific RNA synthesis[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[Target]

Human Endogenous Metabolite

[References]

[1]. B B Goswami, et al. Inhibition of vaccinia virus growth and virus-specific RNA synthesis by 3'-O-methyl adenosine and 3'-O-methyl guanosine. J Virol. 1983 Mar;45(3):1164-7.

Chemical & Physical Properties

[ Density]:
1.98g/cm3

[ Boiling Point ]:
711.7ºC at 760mmHg

[ Molecular Formula ]:
C₁₁H₁₅N₅O₅

[ Molecular Weight ]:
297.26700

[ Flash Point ]:
384.2ºC

[ Exact Mass ]:
297.10700

[ PSA ]:
148.51000

[ Vapour Pressure ]:
2.93E-21mmHg at 25°C

[ Index of Refraction ]:
1.829

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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