DESMOSINE STANDARD

Names

[ CAS No. ]:
10019-68-8

[ Name ]:
DESMOSINE STANDARD

[Synonym ]:
Desmosine chloride

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₄₀ClN₅O₈

[ Molecular Weight ]:
562.05600

[ Exact Mass ]:
561.25700

[ PSA ]:
257.16000

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Urinary desmosine excretion is inversely correlated with the extent of emphysema in patients with chronic obstructive pulmonary disease.

Int. J. Biochem. Cell Biol. 34 , 594-604, (2002)

An enhanced proteolysis of lung interstitium is key event in the pathogenesis of emphysema, a major constituent of chronic obstructive pulmonary disease. To assess whether urinary desmosine and/or hyd...

Elastin degradation and calcification in an abdominal aorta injury model: role of matrix metalloproteinases.

Circulation 110 , 3480-3487, (2004)

Elastin calcification is a widespread feature of vascular pathology, and circumstantial evidence exists for a correlation between elastin degradation and calcification. We hypothesized that matrix met...

Aluminum chloride pretreatment of elastin inhibits elastolysis by matrix metalloproteinases and leads to inhibition of elastin-oriented calcification.

Am. J. Pathol. 159 , 1981-1986, (2001)

Calcification of elastin occurs in many pathological cardiovascular diseases including atherosclerosis. We have previously shown that purified elastin when subdermally implanted in rats undergoes seve...