结构式 物理化学性质
常用名 7-氨基-3-(1-甲基-1H-四唑-5-硫代甲基)-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯-2-羧酸 英文名 7-Amino-3-(1-methyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid
CAS号 24209-38-9 分子量 328.37100
密度 5.67 g/mL at 25 °C(lit.) 沸点 695.2ºC at 760 mmHg
分子式 C10H12N6O3S2 熔点 890°C
MSDS N/A 闪点 N/A
 产品用途
【用途一】
头孢哌酮、头孢羟唑的中间体。

 名称
[ 中文名 ]: 7-氨基-3-(1-甲基-1H-四唑-5-硫代甲基)-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯-2-羧酸
[ 英文名 ]: 7-Amino-3-(1-methyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid
[中文别名 ]: 7-氨基-3-(1-甲基-1-吡咯烷鎓基)甲基-2-头孢烯-2-羧酸盐酸盐 | 7-氨基-3-(1-甲基-1H-四唑-5-硫甲基)-3-头孢烯-4-羧酸 | 头孢哌酮中间体 | 7-TMCA,头孢哌酮中间体 | 7-氨基-3-(1-甲基-1H-四唑-5-硫代甲基)-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯-2-羧酸 | 头孢甲肟中间体(7-TMCA) | 头孢甲肟中间体 | 头孢派酮中间体 | 头孢甲肟母核 | 3-(1-甲基-1H-四氮唑-5-基)硫甲基-7-氨基头孢霉烷酸 | (6R,反式)7-氨基-3-[(1-甲基-1H-四氮唑-5-基)硫]甲基-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯羧酸 | 3-{{(1-甲基-1H-四唑-5-基)硫}-7-氨基-头孢烷酸
[英文别名 ]: 7-AMINO-3-([(1-METHYL-TETRAZOLE-5-YL)-THIO]METHYL)-CEPHALOSPORANIC ACID | 7-amino-3-[[(1-methyl-1H-tetrazol-5-yl)-thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | 7-Amino-3-[(1-methyltetrazol-5-yl)-thiomethyl]-cephalosporanic acid | 7-Amino-3-methyl tetrazolyl cephalosporanic acid (7-TMCA) | (6R)-7α-Amino-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | (6R-trans)-7-amino-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | 7-AMINO-3-((1-METHYL-TETRAZOLE-5-YL)-THIOMETHYL)-3-CEPHEM-4-CARBOXYLIC ACID | 7-amino-2-carboxy-3-[(1-methyl-1,2,3,4-tetrazol-5-yl)-thiomethyl]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene | 7-TMCA | Intermediate Cefmenoxime | 7-AMino-3-(cisopropyl-1-alkenyl)-3-epheM-4-arboxylic acid | 3-[[(1-Methyl-1H-tetrazol-5-yl)thio]methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-ene-2-carboxylic acid | (7-TMCA)7-AMino-3-Methyl tetrazolyl cephalosporanic acid | (6R,trans)7-Amino-3-[(1-methyl-1H-tetra-zole-5-yl)thio]methyl-8-oxo-5-thio-1-azabicyclo[4.2.0]oct-2-ene-carboxylic acid | (7R)-3-[(1-Methyl-1H-tetrazole-5-yl)thiomethyl]-7-aminocepham-3-ene-4-carboxylic acid | 7-Amino-3-(1-methylt | 3-[(1-methyltetrazol-5-ylthio)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | 7-AMINO-3-(1-METHYL-5-TETRAZOLYLTHIO)METHYL-3-CEPHEM-4-CARBOXYLIC ACID | 7-AMINO-3-(1-METHYLTETRAZOL-5-YLTHIOMETHYL)-3-CEPHEM-4-CARBOXYLIC ACID | 7-ACA-3-MMT | 7-amino-3-[[(1-methyltetrazol-5-yl)-thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | 7-AMino-3-Methyl tetrazolyl cephalosporanic acid | (6R-trans)-7-amino-3-{[(1-methyl-1H-tetrazol-5-yl)thio]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | 3-(1-Methyl-1H-tetra-zolyl)thiomethyl-7-aminocephalosporanicacid | 7-Amino-3-[(1-methyl-1H-tetrazo-5-yl)thiomethyl]-3-Cephem-4-carboxylic acid | (6R)-7t-amino-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
 物理化学性质
[ 密度 ]: 5.67 g/mL at 25 °C(lit.)
[ 沸点 ]: 695.2ºC at 760 mmHg
[ 熔点 ]: 890°C
[ 分子式 ]: C10H12N6O3S2
[ 分子量 ]: 328.37100
[ 精确质量 ]: 328.04100
[ PSA ]: 177.83000
[ 蒸汽压 ]: 2.75E-20mmHg at 25°C
[ 折射率 ]: 1.956
 安全信息
[ 危害码 (欧洲) ]: T,N
[ 风险声明 (欧洲) ]: R23/25:Toxic by inhalation and if swallowed . R33:Danger of cumulative effects. R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
[ 安全声明 (欧洲) ]: S20/21-S28-S45-S60-S61
[ 危险品运输编码 ]: UN 3283 6.1/PG 3
[ WGK德国 ]: 3
[ 包装等级 ]: III
[ 海关编码 ]: 2934999090
 合成线路

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文献: : US4714760 A1, ;

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文献: : Saikawa; Takano; Momonoi; et al. Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 12 p. 5534 - 5538

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文献: : Journal of Organic Chemistry, , vol. 53, # 5 p. 983 - 991

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文献: : Journal of Organic Chemistry, , vol. 53, # 5 p. 983 - 991

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文献: : Journal of Organic Chemistry, , vol. 53, # 5 p. 983 - 991

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文献: : Journal of Organic Chemistry, , vol. 53, # 5 p. 983 - 991
 海关
[ 海关编码 ]: 2934999090
[ 中文概述 ]: 2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
[申报要素 ]: 品名, 成分含量, 用途
[ Summary ]: 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%