912846-67-4

• 常用中文名：7-氟-6-硝基-3,4-二氢异喹啉-2(1h)-羧酸叔丁酯
• 常用英文名：tert-Butyl 7-fluoro-6-nitro-3,4-dihydroisoquinoline-2(1H)-carboxylate
• CAS号：912846-67-4
• 分子式：C₁₄H₁₇FN₂O₄
• 分子量：296.29400
• 发布时间：2018-12-04 19:44:12
• 更新时间：2024-01-05 09:54:38

名称

• 中文名: 7-氟-6-硝基-3,4-二氢异喹啉-2(1h)-羧酸叔丁酯
• 英文名: tert-butyl 7-fluoro-6-nitro-3,4-dihydro-1H-isoquinoline-2-carboxylate
• 英文别名: 1,1-dimethylethyl 7-fluoro-6-nitro-3,4-dihydro-2(1H)-isoquinolinecarboxylate; tert-Butyl 7-fluoro-6-nitro-3,4-dihydroisoquinoline-2(1H)-carboxylate

物化性质

• 分子式: C₁₄H₁₇FN₂O₄
• 分子量: 296.29400
• 精确质量: 296.11700
• PSA: 75.36000
• LogP: 3.48820
• 储存条件: 2-8°C，干燥密封

安全

• 海关编码: 2933499090

合成路线

912846-66-3 24424-99-5 ~% 912846-67-4

文献：GLAXO GROUP LIMITED Patent: WO2006/108709 A1, 2006 ; Location in patent: Page/Page column 51 ; WO 2006/108709 A1

912878-83-2 24424-99-5 ~77% 912846-67-4

文献：Watson, Nigel S.; Adams, Carl; Belton, David; Brown, David; Burns-Kurtis, Cynthia L.; Chaudry, Laiq; Chan, Chuen; Convery, Maire A.; Davies, David E.; Exall, Anne M.; Harling, John D.; Irvine, Stephanie; Irving, Wendy R.; Kleanthous, Savvas; McLay, Iain M.; Pateman, Anthony J.; Patikis, Angela N.; Roethke, Theresa J.; Senger, Stefan; Stelman, Gary J.; Toomey, John R.; West, Robert I.; Whittaker, Caroline; Zhou, Ping; Young, Robert J. Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 6 p. 1588 - 1592

912846-63-0 ~% 912846-67-4

文献：Watson, Nigel S.; Adams, Carl; Belton, David; Brown, David; Burns-Kurtis, Cynthia L.; Chaudry, Laiq; Chan, Chuen; Convery, Maire A.; Davies, David E.; Exall, Anne M.; Harling, John D.; Irvine, Stephanie; Irving, Wendy R.; Kleanthous, Savvas; McLay, Iain M.; Pateman, Anthony J.; Patikis, Angela N.; Roethke, Theresa J.; Senger, Stefan; Stelman, Gary J.; Toomey, John R.; West, Robert I.; Whittaker, Caroline; Zhou, Ping; Young, Robert J. Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 6 p. 1588 - 1592

912846-65-2 ~% 912846-67-4

文献：Watson, Nigel S.; Adams, Carl; Belton, David; Brown, David; Burns-Kurtis, Cynthia L.; Chaudry, Laiq; Chan, Chuen; Convery, Maire A.; Davies, David E.; Exall, Anne M.; Harling, John D.; Irvine, Stephanie; Irving, Wendy R.; Kleanthous, Savvas; McLay, Iain M.; Pateman, Anthony J.; Patikis, Angela N.; Roethke, Theresa J.; Senger, Stefan; Stelman, Gary J.; Toomey, John R.; West, Robert I.; Whittaker, Caroline; Zhou, Ping; Young, Robert J. Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 6 p. 1588 - 1592

912846-64-1 ~% 912846-67-4

文献：Watson, Nigel S.; Adams, Carl; Belton, David; Brown, David; Burns-Kurtis, Cynthia L.; Chaudry, Laiq; Chan, Chuen; Convery, Maire A.; Davies, David E.; Exall, Anne M.; Harling, John D.; Irvine, Stephanie; Irving, Wendy R.; Kleanthous, Savvas; McLay, Iain M.; Pateman, Anthony J.; Patikis, Angela N.; Roethke, Theresa J.; Senger, Stefan; Stelman, Gary J.; Toomey, John R.; West, Robert I.; Whittaker, Caroline; Zhou, Ping; Young, Robert J. Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 6 p. 1588 - 1592

1583-88-6 ~% 912846-67-4

文献：Watson, Nigel S.; Adams, Carl; Belton, David; Brown, David; Burns-Kurtis, Cynthia L.; Chaudry, Laiq; Chan, Chuen; Convery, Maire A.; Davies, David E.; Exall, Anne M.; Harling, John D.; Irvine, Stephanie; Irving, Wendy R.; Kleanthous, Savvas; McLay, Iain M.; Pateman, Anthony J.; Patikis, Angela N.; Roethke, Theresa J.; Senger, Stefan; Stelman, Gary J.; Toomey, John R.; West, Robert I.; Whittaker, Caroline; Zhou, Ping; Young, Robert J. Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 6 p. 1588 - 1592

上下游产品

上游产品  4
912846-66-3 24424-99-5 912878-83-2 1583-88-6
下游产品  1
912846-68-5

海关

海关编码	2933499090
中文概述	2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%