CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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QL3410000
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CHEMICAL NAME :
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2-Naphthol, 1-chloro-
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CAS REGISTRY NUMBER :
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633-99-8
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BEILSTEIN REFERENCE NO. :
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1939233
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LAST UPDATED :
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199612
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DATA ITEMS CITED :
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3
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MOLECULAR FORMULA :
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C10-H7-Cl-O
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MOLECULAR WEIGHT :
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178.62
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WISWESSER LINE NOTATION :
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L66J BG CQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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2310 mg/kg
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TOXIC EFFECTS :
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Behavioral - withdrawal Gastrointestinal - changes in structure or function of salivary glands
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REFERENCE :
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GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 32(4),55,1988
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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580 mg/kg
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TOXIC EFFECTS :
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Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity
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REFERENCE :
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GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 32(4),55,1988
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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275 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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IJPAAO Indian Journal of Pharmacy. (Bombay, India) V.1-40(1), 1939-78. For publisher information, see IJSIDW. Volume(issue)/page/year: 30,89,1968
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