35700-21-1

• 常用中文名：15(S)-15-甲基前列腺素F2α甲酯
• 常用英文名：Carboprost Methyl
• CAS号：35700-21-1
• 分子式：C₂₂H₃₈O₅
• 分子量：382.534
• 发布时间：2018-08-17 18:19:28
• 更新时间：2023-01-14 21:54:05

名称

• 中文名: 15(S)-15-甲基前列腺素
• 英文名: 15(S)-15-Methyl prostaglandin
• 英文别名: Methyl (5Z,9α,11α,13E,15S)-9,11,15-trihydroxy-15-methylprosta-5,13-dien-1-oate; 15-methyl-prostaglandinf2-alphamethylester; 15-methyl-pgf2-alphamethylester; Carboprost methyl ester; (15S)-15-Methylprostaglandin F2a Methyl Ester; 15(S)-15-Methyl-pgf2a Methyl Ester; 15M-PGF2a; 15(s)15-methyl-pgf2-alphamethylester; Carboprost Methyl; U-36384; METHYL CARBOPROST; Methyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((E)-(3S)-3-hydroxy-3-methyl-1-octenyl)cyclopentyl)-5-heptenoate; Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-15-methyl-, methyl ester, (5Z,9α,11α,13R,15S)-; Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-15-methyl-, methyl ester, (5Z,9α,11α,13E,15S)-; methyl (Z)-7-(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-((3S)-3-hydroxy-3-methyl-1-octenyl)cyclopentyl]-5-heptenoate

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 501.7±50.0 °C at 760 mmHg
• 分子式: C₂₂H₃₈O₅
• 分子量: 382.534
• 闪点: 162.2±23.6 °C
• 精确质量: 382.271912
• PSA: 86.99000
• LogP: 3.05
• 蒸汽压: 0.0±2.9 mmHg at 25°C
• 折射率: 1.545

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : MJ9654500 CHEMICAL NAME : 5-Heptenoic acid, 7-(3,5-dihydroxy-2-(3-hydroxy-3(S)-methyl-1-octenyl)c yclopentyl)-, methyl ester CAS REGISTRY NUMBER : 35700-21-1 LAST UPDATED : 198910 DATA ITEMS CITED : 10 MOLECULAR FORMULA : C22-H38-O5 MOLECULAR WEIGHT : 382.60 WISWESSER LINE NOTATION : L5TJ AQ B2U4VO1 C1U1XQ5&1 DQ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravaginal DOSE : 60 ug/kg SEX/DURATION : female 16 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - abortion REFERENCE : PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1972- Volume(issue)/page/year: 16,143,1978 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravaginal DOSE : 10 ug/kg SEX/DURATION : female 10 week(s) after conception TOXIC EFFECTS : Reproductive - Fertility - abortion REFERENCE : CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 27,51,1983 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravaginal DOSE : 60 ug/kg SEX/DURATION : female 7 week(s) after conception TOXIC EFFECTS : Reproductive - Fertility - abortion REFERENCE : CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 22,57,1980 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravaginal DOSE : 50 ug/kg SEX/DURATION : female 37 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - abortion REFERENCE : AJOGAH American Journal of Obstetrics and Gynecology. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1920- Volume(issue)/page/year: 124,495,1976 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravaginal DOSE : 78 ug/kg SEX/DURATION : female 25 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - other measures of fertility REFERENCE : OBGNAS Obstetrics and Gynecology. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1953- Volume(issue)/page/year: 48,221,1976 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Implant DOSE : 4400 ug/kg SEX/DURATION : male 84 day(s) pre-mating TOXIC EFFECTS : Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females) REFERENCE : FESTAS Fertility and Sterility. (American Fertility Soc., 608 13th Ave. S, Birmingham, AL 35282) V.1- 1950- Volume(issue)/page/year: 29,109,1978 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Implant DOSE : 16800 ug/kg SEX/DURATION : male 84 day(s) pre-mating TOXIC EFFECTS : Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands REFERENCE : FESTAS Fertility and Sterility. (American Fertility Soc., 608 13th Ave. S, Birmingham, AL 35282) V.1- 1950- Volume(issue)/page/year: 29,109,1978 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intratesticular DOSE : 4400 ug/kg SEX/DURATION : male 20 day(s) pre-mating TOXIC EFFECTS : Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands REFERENCE : FESTAS Fertility and Sterility. (American Fertility Soc., 608 13th Ave. S, Birmingham, AL 35282) V.1- 1950- Volume(issue)/page/year: 29,103,1978 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intratesticular DOSE : 16800 ug/kg SEX/DURATION : male 20 day(s) pre-mating TOXIC EFFECTS : Reproductive - Paternal Effects - testes, epididymis, sperm duct REFERENCE : FESTAS Fertility and Sterility. (American Fertility Soc., 608 13th Ave. S, Birmingham, AL 35282) V.1- 1950- Volume(issue)/page/year: 29,103,1978 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 4 ug/kg SEX/DURATION : female 4 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated) REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 186,67,1973

安全

• 海关编码: 2918990090

海关

海关编码	2918990090
中文概述	2918990090. 其他含其他附加含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%