676560-01-3

• 常用中文名：6-氟烟酸叔丁酯
• 常用英文名：3-Pyridinecarboxylic acid, 6-fluoro-, 1,1-dimethylethyl ester
• CAS号：676560-01-3
• 分子式：C₁₀H₁₂FNO₂
• 分子量：197.20600
• 发布时间：2018-07-23 16:10:07
• 更新时间：2024-01-05 08:03:26

名称

• 中文名: 6-氟烟酸叔丁酯
• 英文名: tert-butyl 6-fluoropyridine-3-carboxylate
• 英文别名: tert-Butyl 6-fluoronicotinate; 3-Pyridinecarboxylic acid,6-fluoro-,1,1-dimethylethyl ester; 6-fluoronicotinic acid tert-butyl ester

物化性质

• 分子式: C₁₀H₁₂FNO₂
• 分子量: 197.20600
• 精确质量: 197.08500
• PSA: 39.19000
• LogP: 2.17600
• 储存条件: 室温，保存在惰性气体中

合成路线

403-45-2 75-65-0 ~% 676560-01-3

文献：ABBOTT LABORATORIES Patent: WO2004/26822 A2, 2004 ; Location in patent: Page 63 ; WO 2004/026822 A2

403-45-2 75-65-0 36805-97-7 ~% 676560-01-3

文献：Madar, David J.; Djuric, Stevan W.; Michmerhuizen, Melissa J.; Kopecka, Hana A.; Li, Xiaofeng; Longenecker, Kenton L.; Pei, Zhonghua; Pireh, Daisy; Sham, Hing L.; Stewart, Kent D.; Szczepankiewicz, Bruce G.; Wiedeman, Paul E.; Yong, Hong Patent: US2004/259843 A1, 2004 ; Title/Abstract Full Text Show Details Madar, David J.; Djuric, Stevan W.; Michmerhuizen, Melissa J.; Kopecka, Hana A.; Li, Xiaofeng; Longenecker, Kenton L.; Pei, Zhonghua; Pireh, Daisy; Sham, Hing L.; Stewart, Kent D.; Szczepankiewicz, Bruce G.; Wiedeman, Paul E.; Yong, Hong Patent: US2005/215784 A1, 2005 ; US 20050215784 A1

403-45-2 36805-97-7 ~% 676560-01-3

文献：Madar, David J.; Kopecka, Hana; Pireh, Daisy; Yong, Hong; Pei, Zhonghua; Li, Xiaofeng; Wiedeman, Paul E.; Djuric, Stevan W.; Von Geldern, Thomas W.; Fickes, Michael G.; Bhagavatula, Lakshmi; McDermott, Todd; Wittenberger, Steven; Richards, Steven J.; Longenecker, Kenton L.; Stewart, Kent D.; Lubben, Thomas H.; Ballaron, Stephen J.; Stashko, Michael A.; Long, Michelle A.; Wells, Heidi; Zinker, Bradley A.; Mika, Amanda K.; Beno, David W. A.; Kempf-Grote, Anita J.; Polakowski, James; Segreti, Jason; Reinhart, Glenn A.; Fryer, Ryan M.; Sham, Hing L.; Trevillyan, James M. Journal of Medicinal Chemistry, 2006 , vol. 49, # 21 p. 6416 - 6420

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