149281-42-5

• 常用中文名：6-氯-N-甲氧基-N-甲基烟酰胺
• 常用英文名：6-Chloro-N-methoxy-N-methylnicotinamide
• CAS号：149281-42-5
• 分子式：C₈H₉ClN₂O₂
• 分子量：200.622
• 发布时间：2018-11-22 17:37:44
• 更新时间：2024-01-02 19:59:34

名称

• 中文名: 6-氯-n-甲氧基-n-甲基烟酰胺
• 英文名: 6-chloro-N-methoxy-N-methylpyridine-3-carboxamide
• 中文别名: N-甲氧基-N-甲基-6-氯-3-吡啶甲酰胺
• 英文别名: 2-Chloro-5-(N-methyl-N-methoxycarbamoyl)pyridine; N-Methoxy-N-Methyl-6-chloronicotinamide; 6-chloro-N-methoxy-N-methylpyridin-3-carboxamide; chloromethoxymethylnicotinamide; 6-chloro-N-methyl-N-(methyloxy)-3-pyridinecarboxamide; 6-Chloro-N-methoxy-N-methylnicotinamide; IJUKASNMWCZHHA-UHFFFAOYSA; 3-Pyridinecarboxamide,6-chloro-N-methoxy-N-methyl; 3-Pyridinecarboxamide, 6-chloro-N-methoxy-N-methyl-

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 365.3±27.0 °C at 760 mmHg
• 分子式: C₈H₉ClN₂O₂
• 分子量: 200.622
• 闪点: 174.8±23.7 °C
• 精确质量: 200.035248
• PSA: 42.43000
• LogP: 1.20
• 蒸汽压: 0.0±0.8 mmHg at 25°C
• 折射率: 1.544
• 储存条件: 室温

合成路线

58757-38-3 6638-79-5 ~97% 149281-42-5

文献：Dehmlow, Henrietta; Aebi, Johannes D.; Jolidon, Synese; Ji, Yu-Hua; Von der Mark, Elisabeth M.; Himber, Jacques; Morand, Olivier H. Journal of Medicinal Chemistry, 2003 , vol. 46, # 15 p. 3354 - 3370

5326-23-8 6638-79-5 ~95% 149281-42-5

文献：PFIZER PRODUCTS INC.? Patent: WO2005/60967 A1, 2005 ; Location in patent: Page/Page column 21 ; WO 2005/060967 A1

58757-38-3 1117-97-1 ~89% 149281-42-5

文献：ABBOTT GMBH and; CO. KG; TURNER, Sean Colm; BAKKER, Margaretha Henrica Maria; HORNBERGER, Wilfried; WOLTER, Falko Ernst Patent: WO2010/109005 A1, 2010 ; Location in patent: Page/Page column 54 ;

73781-91-6 6638-79-5 ~% 149281-42-5

文献：WO2005/118542 A1, ; Page/Page column 85-86 ; WO 2005/118542 A1

5326-23-8 ~% 149281-42-5

文献：Journal of Medicinal Chemistry, , vol. 46, # 15 p. 3354 - 3370

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