53617-36-0

• 常用中文名：1-甲基-4-(4-哌啶基)哌嗪
• 常用英文名：1-Methyl-4-(4-piperidinyl)piperazine
• CAS号：53617-36-0
• 分子式：C₁₀H₂₁N₃
• 分子量：183.294
• 发布时间：2018-12-25 16:26:59
• 更新时间：2024-01-02 22:39:31
• 下载msds

名称

• 中文名: 1-甲基-4-(4-哌啶基)哌嗪
• 英文名: 1-methyl-4-(piperidin-4-yl)-piperazine
• 中文别名: 1-甲基-4-(哌啶-4-基)哌嗪(盐酸盐); 1-甲基-4-(哌啶基-4-YL)哌嗪; 1-甲基-4-(哌啶基)哌嗪
• 英文别名: (1-methyl-4-piperidin-4-yl)-piperazine; 1-Methyl-4-(4-piperidinyl)piperazine; Piperazine, 1-methyl-4-(4-piperidinyl)-; MFCD03274729; 1-Methyl-4-piperidin-4-yl-piperazine; 1-Methyl-4-(piperidin-4-yl)piperazine

物化性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 260.9±8.0 °C at 760 mmHg
• 熔点: 53-56°C
• 分子式: C₁₀H₂₁N₃
• 分子量: 183.294
• 闪点: 113.9±13.1 °C
• 精确质量: 183.173553
• PSA: 18.51000
• LogP: -0.41
• 蒸汽压: 0.0±0.5 mmHg at 25°C
• 折射率: 1.504
• 储存条件:

  保持贮藏器密封、储存在阴凉、干燥的地方，确保工作间有良好的通风或排气装置

• 稳定性:

  如果遵照规格使用和储存则不会分解，未有已知危险反应

• 计算化学:

  1.疏水参数计算参考值（XlogP）:0.2

  2.氢键供体数量:1

  3.氢键受体数量:3

  4.可旋转化学键数量:1

  5.互变异构体数量:无

  6.拓扑分子极性表面积18.5

  7.重原子数量:13

  8.表面电荷:0

  9.复杂度:146

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1. 性状：未确定

  2. 密度（g/mL,20ºC）：未确定

  3. 相对蒸汽密度（g/mL,空气=1）： 未确定

  4. 熔点（ºC）：53-56

  5. 沸点（ºC）：未确定

  6. 沸点（ºC，5mm hg）：未确定

  7. 折射率：未确定

  8. 闪点（°C）：未确定

  9. 比旋光度（ºC）：未确定

  10. 自燃点或引燃温度（ºC）： 未确定

  11. 蒸气压（kPa,20ºC）：未确定

  12. 饱和蒸气压（kPa,60ºC）：未确定

  13. 燃烧热（KJ/mol）：未确定

  14. 临界温度（ºC）：未确定

  15. 临界压力（KPa）：未确定

  16. 油水（辛醇/水）分配系数的对数值：未确定

  17. 爆炸上限（%,V/V）：未确定

  18. 爆炸下限（%,V/V）：未确定

  19. 溶解性：未确定

MSDS

Name: 1(1-Methylpiperidin-4-yl)piperazine Material Safety Data Sheet Synonym: CAS: 53617-36-0 Section 1 - Chemical Product MSDS Name:1(1-Methylpiperidin-4-yl)piperazine Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 53617-36-0 1(1-Methylpiperidin-4-yl)piperazine unlisted Hazard Symbols: C Risk Phrases: 20/21/22 34 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful by inhalation, in contact with skin and if swallowed. Causes burns. Potential Health Effects Eye: Causes eye burns. Skin: Harmful if absorbed through the skin. Causes skin burns. Ingestion: Harmful if swallowed. Causes gastrointestinal tract burns. Inhalation: Harmful if inhaled. Causes chemical burns to the respiratory tract. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Do not induce vomiting. Get medical aid immediately. Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use dry chemical or foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Section 7 - HANDLING and STORAGE Handling: Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood. Storage: Store in a cool, dry place. Store in a tightly closed container. Corrosives area. Store under nitrogen. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 53617-36-0: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Oil Color: pale-yellow Odor: amine-like pH: >7 Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: 100 deg C Freezing/Melting Point: Not available. Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: almost insoluble Specific Gravity/Density: Molecular Formula: C10H21N3 Molecular Weight: 183.3 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials, prolonged exposure to air. Incompatibilities with Other Materials: Strong oxidizing agents, carbon dioxide. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 53617-36-0 unlisted. LD50/LC50: Not available. Carcinogenicity: 1(1-Methylpiperidin-4-yl)piperazine - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: CORROSIVE LIQUID, TOXIC, N.O.S.* Hazard Class: 8 (6.1) UN Number: 2922 Packing Group: III IMO Shipping Name: CORROSIVE LIQUID, TOXIC, N.O.S. Hazard Class: 8 (6.1) UN Number: 2922 Packing Group: III RID/ADR Shipping Name: CORROSIVE LIQUID, TOXIC, N.O.S. Hazard Class: 8 (6.1) UN Number: 2922 Packing group: III Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: C Risk Phrases: R 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. R 34 Causes burns. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 53617-36-0: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 53617-36-0 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 53617-36-0 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

生态学数据: 对水是稍微有危害的不要让未稀释或大量的产品接触地下水、水道或者污水系统，若无政府许可，勿将材料排入周围环境。

安全

• 危害码 (欧洲): Xi
• 危险品运输编码: 3259.0
• 危险类别: 8.0
• 海关编码: 2933599090

海关

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%