157327-43-0

• 常用中文名：3-乙酰基-4-氧代-1-哌啶羧酸-1,1-二甲基乙酯
• 常用英文名：tert-butyl 3-acetyl-4-oxopiperidine-1-carboxylate
• CAS号：157327-43-0
• 分子式：C₁₂H₁₉NO₄
• 分子量：241.28400
• 发布时间：2018-12-30 23:23:17
• 更新时间：2024-01-11 19:38:20

名称

• 中文名: 3-乙酰基-4-氧代-1-哌啶羧酸-1,1-二甲基乙酯
• 英文名: tert-butyl 3-acetyl-4-oxopiperidine-1-carboxylate
• 英文别名: rac-3-acetyl-4-oxo-piperidine-1-carboxylic acid tert-butyl-ester; 1,1-dimethylethyl 3-acetyl-4-oxo-1-piperidinecarboxylate; 3-acetyl-1-Boc-4-oxopiperidine

物化性质

• 分子式: C₁₂H₁₉NO₄
• 分子量: 241.28400
• 精确质量: 241.13100
• PSA: 63.68000
• LogP: 1.33940

安全

• 海关编码: 2933399090

合成路线

2466-76-4 79099-07-3 ~% 157327-43-0

文献：SUNSHINE LAKE PHARMA CO., LTD.; ZHANG, Jiancun; ZHANG, Yingjun; ZHANG, Weihong; LIU, Bing; ZHANG, Jiquan; LIU, Jinlei; ZHANG, Lu Patent: WO2013/71697 A1, 2013 ; Location in patent: Paragraph 00305 ;

79099-07-3 108-24-7 ~88% 157327-43-0

文献：GLAXO GROUP LIMITED; BAILEY, James, Matthew; BROWN, John, Alexander; DEMONT, Emmanuel, Hubert; SEAL, Gail, Astra, Lorraine; SMETHURST, Christian, Alan, Paul; WITHERINGTON, Jason; HARRISON, Lee, Andrew Patent: WO2010/146104 A1, 2010 ; Location in patent: Page/Page column 28-29 ; WO 2010/146104 A1

79099-07-3 141-78-6 ~16% 157327-43-0

文献：Wang, Pu-Sheng; Zhou, Xiao-Le; Gong, Liu-Zhu Organic Letters, 2014 , vol. 16, # 3 p. 976 - 979

2466-76-4 ~% 157327-43-0

文献：ACTELION PHARMACEUTICALS LTD. Patent: WO2005/23781 A1, 2005 ; Location in patent: Page/Page column 37 ; WO 2005/023781 A1

24424-99-5 ~% 157327-43-0

文献：SUNSHINE LAKE PHARMA CO., LTD.; ZHANG, Jiancun; ZHANG, Yingjun; ZHANG, Weihong; LIU, Bing; ZHANG, Jiquan; LIU, Jinlei; ZHANG, Lu Patent: WO2013/71697 A1, 2013 ;

109384-19-2 ~% 157327-43-0

文献：SUNSHINE LAKE PHARMA CO., LTD.; ZHANG, Jiancun; ZHANG, Yingjun; ZHANG, Weihong; LIU, Bing; ZHANG, Jiquan; LIU, Jinlei; ZHANG, Lu Patent: WO2013/71697 A1, 2013 ;

5382-16-1 ~% 157327-43-0

文献：SUNSHINE LAKE PHARMA CO., LTD.; ZHANG, Jiancun; ZHANG, Yingjun; ZHANG, Weihong; LIU, Bing; ZHANG, Jiquan; LIU, Jinlei; ZHANG, Lu Patent: WO2013/71697 A1, 2013 ;

79099-07-3 ~% 157327-43-0

文献：Yogeeswari, Perumal; Sharma, Monika; Samala, Ganesh; Gangadhar, Matharasala; Karthick, Srirama; Mallipeddi, Saketh; Semwal, Arvind; Sriram, Dharmarajan European Journal of Medicinal Chemistry, 2013 , vol. 66, p. 211 - 220

上下游产品

上游产品  7
2466-76-4 79099-07-3 108-24-7 141-78-6
24424-99-5 109384-19-2 5382-16-1
下游产品  1
733757-77-2

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%