13256-22-9

• 常用中文名：N-亚硝基肌氨酸
• 常用英文名：[Methyl(nitroso)amino]acetic acid
• CAS号：13256-22-9
• 分子式：C₃H₆N₂O₃
• 分子量：118.091
• 发布时间：2017-01-19 02:13:18
• 更新时间：2024-01-02 16:35:18

名称

• 中文名: N-亚硝基肌氨酸
• 英文名: N-nitrososarcosine
• 英文别名: Acetic acid, 2-(methylnitrosoamino)-; N-Nitrososarcosine; 2-[methyl(nitroso)amino]acetic acid; [Methyl(nitroso)amino]acetic acid

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 353.1±25.0 °C at 760 mmHg
• 熔点: 66-67ºC
• 分子式: C₃H₆N₂O₃
• 分子量: 118.091
• 闪点: 167.4±23.2 °C
• 精确质量: 118.037842
• PSA: 69.97000
• LogP: -1.00
• 外观性状: 米白色至浅黄色固体
• 蒸汽压: 0.0±1.7 mmHg at 25°C
• 折射率: 1.504
• 储存条件: 20°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : VQ3150000 CHEMICAL NAME : Sarcosine, N-nitroso- CAS REGISTRY NUMBER : 13256-22-9 BEILSTEIN REFERENCE NO. : 1756162 LAST UPDATED : 199612 DATA ITEMS CITED : 11 MOLECULAR FORMULA : C3-H6-N2-O3 MOLECULAR WEIGHT : 118.11 WISWESSER LINE NOTATION : QV1N1&NO HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >5 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NATWAY Naturwissenschaften. (Springer-Verlag, Heidelberger Platz 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1913- Volume(issue)/page/year: 50,100,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 184 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,1981,1975 ** TUMORIGENIC DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 29 gm/kg/41W-C TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 19,1077,1969 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 118 gm/kg/56W-C TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Ear) - effect, not otherwise specified Lungs, Thorax, or Respiration - tumors REFERENCE : FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 33,596,1974 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 17,327,1978 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 17,327,1978 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FRANCE;Carcinogen JAN 1993

安全

• 危害码 (欧洲): Xn
• 危险品运输编码: UN 2811
• 包装等级: III
• 危险类别: 6.1(b)

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