869631-11-8

• 常用中文名：O-去乙基坎地沙坦
• 常用英文名：O-Desethyl candesartan cilexetil
• CAS号：869631-11-8
• 分子式：C₃₁H₃₀N₆O₆
• 分子量：582.60600
• 发布时间：2018-06-17 12:08:52
• 更新时间：2024-01-11 14:46:38

名称

• 中文名: O-去乙基坎地沙坦
• 英文名: 1-cyclohexyloxycarbonyloxyethyl 2-oxo-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1H-benzimidazole-4-carboxylate
• 英文别名: 2-oxocandesartan cilexetil; UNII-JC6R5VA63B; desethyl-condesartan; 2,3-Dihydro-2-oxo-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-4-carboxylic Acid 1-[[(Cyclohexyloxy)carbonyl]oxy]ethyl Ester; CNS-desethyl; desethyl-CNS; 1-{[(cyclohexyloxy)carbonyl]oxy}ethyl 3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-2-oxo-2,3-dihydro-1H-benzimidazole-4-carboxylate; O-Desethyl Candesartan Cilexetil; Candesartan Cilexetil Impurity 2

物化性质

• 分子式: C₃₁H₃₀N₆O₆
• 分子量: 582.60600
• 精确质量: 582.22300
• PSA: 154.34000
• LogP: 5.62600

安全

• 危险品运输编码: NONH for all modes of transport

合成路线

170791-09-0 ~% 869631-11-8 145040-37-5

文献：KRKA, D.D. NOVO MESTO Patent: WO2007/42161 A1, 2007 ; Location in patent: Page/Page column 16-17 ;

145040-37-5 ~88% 869631-11-8

文献：Havllcek, Jaroslav; Mandelova, Zuzana; Weisemann, Ruediger; Strelec, Ivo; Placek, Lukas; Radl, Stanislav Collection of Czechoslovak Chemical Communications, 2009 , vol. 74, # 2 p. 347 - 362

170791-09-0 ~70% 869631-11-8

文献：Havllcek, Jaroslav; Mandelova, Zuzana; Weisemann, Ruediger; Strelec, Ivo; Placek, Lukas; Radl, Stanislav Collection of Czechoslovak Chemical Communications, 2009 , vol. 74, # 2 p. 347 - 362

145040-37-5 ~% 869631-11-8 914613-36-8

文献：TEVA PHARMACEUTICAL INDUSTRIES LTD.; TEVA PHARMACEUTICALS USA, INC. Patent: WO2006/122254 A2, 2006 ; Location in patent: Page/Page column 12; 13 ;

145040-37-5 ~% 869631-11-8 914613-35-7 914613-36-8

文献：TEVA PHARMACEUTICAL INDUSTRIES LTD.; TEVA PHARMACEUTICALS USA, INC. Patent: WO2006/122254 A2, 2006 ; Location in patent: Page/Page column 12; 13 ;

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