868963-98-8

• 常用中文名：2-氨基-5-溴吡啶-3-磺酰氯
• 常用英文名：2-AMINO-5-BROMOPYRIDINE-3-SULFONYLCHLORIDE
• CAS号：868963-98-8
• 分子式：C₅H₄BrClN₂O₂S
• 分子量：271.51900
• 相关类别： 医药中间体 杂环化合物 吡啶类化合物 溴吡啶
• 发布时间：2019-01-01 11:00:14
• 更新时间：2024-01-08 01:54:16

名称

• 中文名: 2-氨基-5-溴吡啶-3-磺酰氯
• 英文名: 2-amino-5-bromopyridine-3-sulfonyl chloride
• 英文别名: 2-amino-5-bromo-3-pyridinesulfonylchloride; I02-2810; QC-5399; 2-amino-5-bromopyridine-3-sulphonyl chloride; 2-Amino-5-bromopyridine-3-sulfonylchloride

物化性质

• 密度: 1.97
• 沸点: 284.2ºC at 760 mmHg
• 分子式: C₅H₄BrClN₂O₂S
• 分子量: 271.51900
• 闪点: 125.7ºC
• 精确质量: 269.88700
• PSA: 81.43000
• LogP: 3.01580

合成路线

1072-97-5 ~77% 868963-98-8

文献：SMITHKLINE BEECHAM CORPORATION Patent: WO2008/157191 A2, 2008 ; Location in patent: Page/Page column 74 ; WO 2008/157191 A2

1072-97-5 7790-94-5 ~% 868963-98-8

文献：PETER MACCALLUM CANCER INSTITUTE; SPICER, Julie Ann; DENNY, William Alexander; MILLER, Christian Karl; O'CONNOR, Patrick David; HUTTUNEN, Kristiina; TRAPANI, Joseph A.; HILL, Geoff; ALEXANDER, Kylie Patent: WO2014/28968 A1, 2014 ; Location in patent: Page/Page column 98 ;

38875-53-5 ~% 868963-98-8

文献：Leahy, James W.; Buhr, Chris A.; Johnson, Henry W. B.; Kim, Byung Gyu; Baik, Taegon; Cannoy, Jonah; Forsyth, Timothy P.; Jeong, Joon Won; Lee, Matthew S.; Ma, Sunghoon; Noson, Kevin; Wang, Longcheng; Williams, Matthew; Nuss, John M.; Brooks, Eric; Foster, Paul; Goon, Leanne; Heald, Nathan; Holst, Charles; Jaeger, Christopher; Lam, Scott; Lougheed, Julie; Nguyen, Lam; Plonowski, Arthur; Song, Joanne; Stout, Thomas; Wu, Xiang; Yakes, Michael F.; Yu, Peiwen; Zhang, Wentao; Lamb, Peter; Raeber, Olivia Journal of Medicinal Chemistry, 2012 , vol. 55, # 11 p. 5467 - 5482

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