179250-28-3

• 常用中文名：2-(4-N-Boc-哌嗪)苄基乙醇
• 常用英文名：2-(4-N-BOC-PIPERAZINYL)BENZYL ALCOHOL
• CAS号：179250-28-3
• 分子式：C₁₆H₂₄N₂O₃
• 分子量：292.37300
• 发布时间：2018-12-28 07:42:37
• 更新时间：2024-01-03 10:36:18

名称

• 中文名: 2-(4-N-Boc-哌嗪)苄基乙醇
• 英文名: tert-butyl 4-[2-(hydroxymethyl)phenyl]piperazine-1-carboxylate

物化性质

• 密度: 1.152g/cm3
• 沸点: 440.9ºC at 760mmHg
• 熔点: 67ºC
• 分子式: C₁₆H₂₄N₂O₃
• 分子量: 292.37300
• 闪点: 220.5ºC
• 精确质量: 292.17900
• PSA: 53.01000
• LogP: 2.23890
• 蒸汽压: 1.5E-08mmHg at 25°C
• 折射率: 1.553

合成路线

174855-57-3 ~75% 179250-28-3

文献：Dyck, Brian; Parker, Jessica; Phillips, Teresa; Carter, Lee; Murphy, Brian; Summers, Robin; Hermann, Julia; Baker, Tracy; Cismowski, Mary; Saunders, John; Goodfellow, Val Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 21 p. 3793 - 3796

444582-90-5 ~% 179250-28-3

文献：Stangeland, Eric L.; Patterson, Lori Jean Patent: US2011/172246 A1, 2011 ; Location in patent: Page/Page column 15 ;

24424-99-5 ~% 179250-28-3

文献：Richardson, Timothy I.; Ornstein, Paul L.; Briner, Karin; Fisher, Matthew J.; Backer, Ryan T.; Biggers, C. Kelly; Clay, Michael P.; Emmerson, Paul J.; Hertel, Larry W.; Hsiung, Hansen M.; Husain, Saba; Kahl, Steven D.; Lee, Jonathan A.; Lindstrom, Terry D.; Martinelli, Michael J.; Mayer, John P.; Mullaney, Jeffery T.; O'Brien, Thomas P.; Pawlak, Joseph M.; Revell, Kevin D.; Shah, Jikesh; Zgombick, John M.; Herr, R. Jason; Melekhov, Alex; Sampson, Peter B.; King, Chi-Hsin R. Journal of Medicinal Chemistry, 2004 , vol. 47, # 3 p. 744 - 755

111373-03-6 ~% 179250-28-3

文献：Richardson, Timothy I.; Ornstein, Paul L.; Briner, Karin; Fisher, Matthew J.; Backer, Ryan T.; Biggers, C. Kelly; Clay, Michael P.; Emmerson, Paul J.; Hertel, Larry W.; Hsiung, Hansen M.; Husain, Saba; Kahl, Steven D.; Lee, Jonathan A.; Lindstrom, Terry D.; Martinelli, Michael J.; Mayer, John P.; Mullaney, Jeffery T.; O'Brien, Thomas P.; Pawlak, Joseph M.; Revell, Kevin D.; Shah, Jikesh; Zgombick, John M.; Herr, R. Jason; Melekhov, Alex; Sampson, Peter B.; King, Chi-Hsin R. Journal of Medicinal Chemistry, 2004 , vol. 47, # 3 p. 744 - 755

446831-27-2 ~% 179250-28-3

文献：Richardson, Timothy I.; Ornstein, Paul L.; Briner, Karin; Fisher, Matthew J.; Backer, Ryan T.; Biggers, C. Kelly; Clay, Michael P.; Emmerson, Paul J.; Hertel, Larry W.; Hsiung, Hansen M.; Husain, Saba; Kahl, Steven D.; Lee, Jonathan A.; Lindstrom, Terry D.; Martinelli, Michael J.; Mayer, John P.; Mullaney, Jeffery T.; O'Brien, Thomas P.; Pawlak, Joseph M.; Revell, Kevin D.; Shah, Jikesh; Zgombick, John M.; Herr, R. Jason; Melekhov, Alex; Sampson, Peter B.; King, Chi-Hsin R. Journal of Medicinal Chemistry, 2004 , vol. 47, # 3 p. 744 - 755

446-52-6 ~% 179250-28-3

文献：Dyck, Brian; Parker, Jessica; Phillips, Teresa; Carter, Lee; Murphy, Brian; Summers, Robin; Hermann, Julia; Baker, Tracy; Cismowski, Mary; Saunders, John; Goodfellow, Val Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 21 p. 3793 - 3796

57260-71-6 ~% 179250-28-3

文献：Dyck, Brian; Parker, Jessica; Phillips, Teresa; Carter, Lee; Murphy, Brian; Summers, Robin; Hermann, Julia; Baker, Tracy; Cismowski, Mary; Saunders, John; Goodfellow, Val Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 21 p. 3793 - 3796

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174855-57-3 444582-90-5 24424-99-5 111373-03-6
446831-27-2 446-52-6 57260-71-6
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