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| 中文名 | 雌二醇二乙酸酯 |
|---|---|
| 英文名 | 17β-Estradiol Diacetate |
| 中文别名 |
3,17-二乙酸-BETA-雌二酯
雌甾-1,3,5(10)-三烯-3,17B-二醇二乙酸酯 |
| 英文别名 | Estradiol diacetate |
| 密度 | 1.17g/cm3 |
|---|---|
| 沸点 | 463.4ºC at 760mmHg |
| 分子式 | C22H28O4 |
| 分子量 | 356.45500 |
| 闪点 | 227.5ºC |
| 精确质量 | 356.19900 |
| PSA | 52.60000 |
| LogP | 4.39970 |
| 折射率 | 1.561 |
|
Section 1. Chemical Product and Company Identification b-Estradiol Diacetate Common Name/ Trade Name Manufacturer Commercial Name(s) Synonym
Chemical Name Chemical Family b-Estradiol Diacetate Section 4. First Aid Measures Eye ContactCheck for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention. Skin ContactIn case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention. Serious Skin ContactWash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek medical attention. InhalationIf inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention. Serious InhalationNot available. IngestionDo NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband. Serious IngestionNot available. Section 5. Fire and Explosion Data Flammability of the Product May be combustible at high temperature. Auto-Ignition Temperature Not available. Flash PointsNot available. Flammable LimitsNot available. Products of CombustionThese products are carbon oxides (CO, CO2). Fire Hazards in Presence of Slightly flammable to flammable in presence of open flames and sparks, of heat. Various SubstancesNon-flammable in presence of shocks. Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available. of Various SubstancesRisks of explosion of the product in presence of static discharge: Not available. Fire Fighting MediaSMALL FIRE: Use DRY chemical powder. and InstructionsLARGE FIRE: Use water spray, fog or foam. Do not use water jet. Special Remarks onNot available. Fire Hazards Special Remarks on Explosion Not available. Hazards Section 6. Accidental Release Measures Small SpillUse appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements. Large SpillUse a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system. b-Estradiol Diacetate Section 7. Handling and Storage PrecautionsKeep locked up.. Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under a fume hood. Ground all equipment containing material. Do not breathe dust. Wear suitable protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment. If you feel unwell, seek medical attention and show the label when possible. Avoid contact with skin and eyes. StorageKeep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 24°C (75.2°F). Section 8. Exposure Controls/Personal Protection Engineering ControlsUse process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Personal ProtectionSplash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used a Large Spillto avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. Exposure LimitsNot available. Section 9. Physical and Chemical Properties Physical state and appearance Solid. (crystalline powder.)OdorNot available. Not available. Taste Molecular Weight356.46 g/mole White to yellowish. Color Not available. pH (1% soln/water) Boiling PointNot available. Melting PointNot available. Critical TemperatureNot available. Specific GravityNot available. Not applicable. Vapor Pressure Vapor DensityNot available. Not available. Volatility Odor ThresholdNot available. Water/Oil Dist. Coeff.Not available. Ionicity (in Water)Not available. Dispersion PropertiesNot available. SolubilityNot available. Section 10. Stability and Reactivity Data StabilityThe product is stable. Instability TemperatureNot available. Conditions of InstabilityExcess heat, light, incompatible materials Incompatibility with variousNot available. substances CorrosivityNot available. b-Estradiol Diacetate Special Remarks onProtect from light and heat. ReactivityNo information incompatilbility with other materials found at this time. Special Remarks onNot available. Corrosivity PolymerizationWill not occur. Section 11. Toxicological Information Routes of EntryInhalation. Ingestion. Toxicity to AnimalsLD50: Not available. LC50: Not available. Chronic Effects on Humans TERATOGENIC EFFECTS: Classified POSSIBLE for human. Other Toxic Effects onHazardous in case of skin contact (irritant), of ingestion, of inhalation. HumansSlightly hazardous in case of skin contact (sensitizer). Special Remarks onNot available. Toxicity to Animals Special Remarks onMay cause adverse reproductive effects (suppresive effects on fertility) and birth defects (teratogenic). Chronic Effects on HumansMay have androgenic and anabolic action. Special Remarks on otherAcute Potential Health Effects: Toxic Effects on HumansSkin: May cause skin irritation. There is a low risk of possible contact dermatitis in sensitized persons. Eyes: May cause eye irritation. Inhalation: May cause mild respiratory tract irritation. Ingestion: May affect cardiovascular system. Section 12. Ecological Information EcotoxicityNot available. BOD5 and CODNot available. Products of BiodegradationPossibly hazardous short term degradation products are not likely. However, long term degradation products may arise. The product itself and its products of degradation are not toxic. Toxicity of the Products of Biodegradation Special Remarks on theNot available. Products of Biodegradation Section 13. Disposal Considerations Waste DisposalWaste must be disposed of in accordance with federal, state and local environmental control regulations. Section 14. Transport Information DOT ClassificationNot a DOT controlled material (United States). Not applicable. Identification Not applicable. Special Provisions for Transport b-Estradiol Diacetate DOT (Pictograms) Section 15. Other Regulatory Information and Pictograms No products were found. Federal and State Regulations California Proposition 65 Warnings Other RegulationsEINECS: This product is on the European Inventory of Existing Commercial Chemical Substances. WHMIS (Canada) Not controlled under WHMIS (Canada). Other Classifications DSCL (EEC)R36/38- Irritating to eyes and skin.S2- Keep out of the reach of children. R63- Possible risk of harm to theS46- If swallowed, seek medical advice unborn child.immediately and show this container or label. Health Hazard HMIS (U.S.A.)2 National Fire Protection 1 Flammability 1 Association (U.S.A.) Fire Hazard 2 0 Reactivity Health Reactivity 0 Specific hazard Personal Protection E WHMIS (Canada) (Pictograms) DSCL (Europe) (Pictograms) TDG (Canada) (Pictograms) ADR (Europe) (Pictograms) Protective Equipment Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. b-Estradiol Diacetate SECTION 16 - ADDITIONAL INFORMATION N/A |
| 危害码 (欧洲) | Xn: Harmful; |
|---|---|
| 风险声明 (欧洲) | 40-48 |
| 安全声明 (欧洲) | 22-24/25 |