68006-83-7

• 常用中文名：2-氨基-3-甲基-9H-吡啶[2,3-b]吲哚
• 常用英文名：2-AMINO-3-METHYL-9H-PYRIDO[2,3-B]INDOLE
• CAS号：68006-83-7
• 分子式：C₁₂H₁₁N₃
• 分子量：197.23600
• 发布时间：2019-02-16 23:29:49
• 更新时间：2024-01-11 02:59:10

名称

• 中文名: 2-氨基-3-甲基-9H-吡啶[2,3-b]吲哚
• 英文名: 3-methyl-9H-pyrido[2,3-b]indol-2-amine
• 中文别名: 2-氨基-3-甲基-9H-吡啶并[2,3-b]吲哚
• 英文别名: Glob-P-1

物化性质

• 密度: 1.334g/cm3
• 沸点: 443.2ºC at 760mmHg
• 熔点: 215-218ºC
• 分子式: C₁₂H₁₁N₃
• 分子量: 197.23600
• 闪点: 252.1ºC
• 精确质量: 197.09500
• PSA: 54.70000
• LogP: 3.18790
• 折射率: 1.806

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UU9354380 CHEMICAL NAME : 9H-Pyrido(2,3-b)indole, 2-amino-3-methyl- CAS REGISTRY NUMBER : 68006-83-7 LAST UPDATED : 199712 DATA ITEMS CITED : 19 MOLECULAR FORMULA : C12-H11-N3 MOLECULAR WEIGHT : 197.26 WISWESSER LINE NOTATION : T B656 FN HMJ D1 EZ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 420 gm/kg/2Y-C TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 32800 mg/kg/85W-C TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Liver - tumors TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 37380 mg/kg/64W-C TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Liver - tumors TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 35424 mg/kg/70W-C TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Liver - tumors TYPE OF TEST : Specific locus test TYPE OF TEST : DNA adduct MUTATION DATA TYPE OF TEST : Cytogenetic analysis TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 125 mg/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 269,79,1992 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 40,253,1986 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 40,253,1986 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

安全

• 危害码 (欧洲): Xi
• 危险品运输编码: UN 2811
• 包装等级: III
• 危险类别: 6.1(b)
• 海关编码: 2933990090

合成路线

134387-50-1 ~79% 68006-83-7

文献：Hibino; Sugino; Kuwada; Ogura; Shintani; Satoh Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 1 p. 79 - 80

126177-54-6 ~% 68006-83-7

文献：Chemical and Pharmaceutical Bulletin, , vol. 39, # 1 p. 79 - 80

134370-12-0 ~% 68006-83-7

文献：Chemical and Pharmaceutical Bulletin, , vol. 39, # 1 p. 79 - 80

36946-70-0 24532-84-1 ~2% 68006-83-7

文献：Matsumoto; Yoshida; Tomita Agricultural and Biological Chemistry, 1981 , vol. 45, # 9 p. 2031 - 2035

上下游产品

上游产品  4
134387-50-1 126177-54-6 36946-70-0 24532-84-1
下游产品  0

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%