40108-12-1

40108-12-1结构式

常用中文名：乙基2-氯-3-氰-6-甲基吡啶-4-羧化物
常用英文名：ethyl 2-chloro-3-cyano-6-methylisonicotinate
CAS号：40108-12-1
分子式：C₁₀H₉ClN₂O₂
分子量：224.64400
相关类别：医药中间体杂环化合物吡啶类化合物乙基吡啶
发布时间：2018-12-22 10:35:07
更新时间：2024-01-02 20:17:55

中文名	2-氯-3-氰基-6-甲基异烟酸乙酯
英文名	ethyl 2-chloro-3-cyano-6-methylpyridine-4-carboxylate
中文别名	2-氯-3-氰基-6甲基吡啶甲酸乙酯乙基2-氯-3-氰-6-甲基吡啶-4-羧化物
英文别名	ethyl-2-chloro-3-cyano-6-methylisonicotinate 2-Chlor-3-cyan-6-methyl-isonicotinsaeure-aethylester ethyl 2-chloro-3-cyano-6-methyl-4-pyridine carboxylate Isonicotinic acid,2-chloro-3-cyano-6-methyl-,ethyl ester Ethyl-2-chloro-3-cyano-6-methylisonicotinate ETHYL 2-CHLORO-3-CYANO-6-METHYLISONICOTINATE 2-chloro-3-cyano-6-methylisonicotinic acid ethyl ester 2-chloro-3-cyano-6-methyl-4-pyridinecarboxylic acid,ethyl ester

密度	1.3g/cm3
沸点	387.7ºC at 760 mmHg
熔点	58ºC
分子式	C₁₀H₉ClN₂O₂
分子量	224.64400
闪点	188.2ºC
精确质量	224.03500
PSA	62.98000
LogP	2.09178
折射率	1.542
储存条件	室温

Name:	Ethyl 2-chloro-3-cyano-6-methylisonicotinate 97% Material Safety Data Sheet
Synonym:
CAS:	40108-12-1

Section 1 - Chemical Product MSDS Name:Ethyl 2-chloro-3-cyano-6-methylisonicotinate 97% Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
40108-12-1	Ethyl 2-chloro-3-cyano-6-methylisonico	97%	unlisted

Hazard Symbols: XN
Risk Phrases: 20/21/22 36/37/38

Section 3 - HAZARDS IDENTIFICATION

EMERGENCY OVERVIEW
Harmful by inhalation, in contact with skin and if swallowed.
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. Harmful if absorbed through the skin.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
Inhalation:
Harmful if inhaled. Causes respiratory tract irritation.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 40108-12-1: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: pale yellow
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 57 - 59 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C10H9ClN2O2
Molecular Weight: 225

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Oxidizing agents, bases, amines, reducing agents, acids.
Hazardous Decomposition Products:
Hydrogen chloride, chlorine, nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 40108-12-1 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Ethyl 2-chloro-3-cyano-6-methylisonicotinate - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: NITRILES, SOLID, TOXIC, N.O.S.*
Hazard Class: 6.1
UN Number: 3276
Packing Group: III
IMO
Shipping Name: NITRILES, TOXIC, N.O.S.
Hazard Class: 6.1
UN Number: 3276
Packing Group: III
RID/ADR
Shipping Name: NITRILES, TOXIC, N.O.S.
Hazard Class: 6.1
UN Number: 3276
Packing group: III

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 20/21/22 Harmful by inhalation, in contact with
skin and if swallowed.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
WGK (Water Danger/Protection)
CAS# 40108-12-1: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 40108-12-1 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 40108-12-1 is not listed on the TSCA inventory.
It is for research and development use only.

SECTION 16 - ADDITIONAL INFORMATION
N/A

危害码 (欧洲)	Xi
风险声明 (欧洲)	R20/21/22;R36/37/38
安全声明 (欧洲)	S26-S36/37/39
危险品运输编码	UN 3439
海关编码	2933399090

上游产品 2
18619-97-1 141-97-9
下游产品 8
56891-69-1 3222-48-8 28900-10-9 859970-50-6
89894-11-1 90915-26-7 59225-10-4 40107-91-3

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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