| 中文名 | 氯化克利西丁 |
|---|---|
| 英文名 | 4-Chloro-2-methoxy-5-methylaniline |
| 中文别名 |
氯化克里西丁
4-氯-2-甲氧基-5-甲基苄胺 |
| 英文别名 |
EINECS 228-943-5
4-Chlor-2-methoxy-5-methyl-anilin ZR DG C1 FO1 Chlorocresidine Benzenamine, 4-chloro-2-methoxy-5-methyl- 2-methoxy-5-methyl-4-chloroaniline 4-Chloro-2-methoxy-5-methylaniline MFCD00007847 o-Anisidine,4-chloro-5-methyl 2-methoxy-4-chloro-5-methylbenzeneamine 4-Chloro-2-methoxy-5-methylbenzenamine 4-chloro-2-methoxy-5-methylphenylamine 5-Chlor-2-amino-p-kresol-methylaether 6-Chlor-3-amino-4-methoxy-1-methyl-benzol 4-chloro-2-methoxy-5-methyl-aniline |
| 密度 | 1.2±0.1 g/cm3 |
|---|---|
| 沸点 | 274.6±35.0 °C at 760 mmHg |
| 熔点 | 102-103 °C(lit.) |
| 分子式 | C8H10ClNO |
| 分子量 | 171.624 |
| 闪点 | 119.9±25.9 °C |
| 精确质量 | 171.045090 |
| PSA | 35.25000 |
| LogP | 2.60 |
| 外观性状 | 黑色结晶固体 |
| 蒸汽压 | 0.0±0.6 mmHg at 25°C |
| 折射率 | 1.565 |
| 储存条件 | 密封储存，储存于阴凉、干燥的库房。 |
| 稳定性 | 避免与不相容材料接触。 与强氧化剂反应。 |
| 计算化学 | 1.疏水参数计算参考值（XlogP）:2.2 2.氢键供体数量:1 3.氢键受体数量:2 4.可旋转化学键数量:1 5.互变异构体数量:无 6.拓扑分子极性表面积35.2 7.重原子数量:11 8.表面电荷:0 9.复杂度:131 10.同位素原子数量:0 11.确定原子立构中心数量:0 12.不确定原子立构中心数量:0 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:1 |
| 更多 | 1. 性状：黑色固体 2. 密度（g/mL,25℃）：未确定 3. 相对蒸汽密度（g/mL,空气=1）：未确定 4. 熔点（ºC）：102-103 5. 沸点（ºC,常压）：未确定 6. 沸点（ºC，17mmHg）：未确定 7. 折射率(n20/D)：未确定 8. 闪点（ºC）：未确定 9. 比旋光度（º）：未确定 10. 自燃点或引燃温度（ºC）：未确定 11. 蒸气压（mmHg,20ºC）：未确定 12. 饱和蒸气压（kPa,25ºC）：未确定 13. 燃烧热（KJ/mol）：未确定 14. 临界温度（ºC）：未确定 15. 临界压力（KPa）：未确定 16. 油水（辛醇/水）分配系数的对数值：未确定 17. 爆炸上限（%,V/V）：未确定 18. 爆炸下限（%,V/V）：未确定 19. 溶解性：未确定 |
Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 20/21/22 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Harmful by inhalation, in contact with skin and if swallowed. Potential Health Effects Eye: May cause eye irritation. Skin: Harmful if absorbed through the skin. Ingestion: Harmful if swallowed. The toxicological properties of this substance have not been fully investigated. Inhalation: Harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 6376-14-3: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Crystals Color: black Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 97 - 103 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: Molecular Weight: 171.63 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Hydrogen chloride, carbon monoxide, oxides of nitrogen, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 6376-14-3 unlisted. LD50/LC50: Not available. Carcinogenicity: 4-Chloro-2-methoxy-5-methylaniline - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.* Hazard Class: 6.1 UN Number: 2811 Packing Group: III IMO Shipping Name: TOXIC SOLID, ORGANIC, N.O.S. Hazard Class: 6.1 UN Number: 2811 Packing Group: III RID/ADR Shipping Name: TOXIC SOLID, ORGANIC, N.O.S. Hazard Class: 6.1 UN Number: 2811 Packing group: III Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. Safety Phrases: S 36/37 Wear suitable protective clothing and gloves. WGK (Water Danger/Protection) CAS# 6376-14-3: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 6376-14-3 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 6376-14-3 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
| 危害码 (欧洲) | Xi:Irritant; |
|---|---|
| 风险声明 (欧洲) | R36/37/38 |
| 安全声明 (欧洲) | S26-S37/39 |
| WGK德国 | 3 |
| 包装等级 | I; II; III |
| 危险类别 | 6.1 |
| 海关编码 | 2922299090 |
|
~%
6376-14-3 |
| 文献：US1930753 , ; |
|
~%
6376-14-3 |
| 文献：Recueil des Travaux Chimiques des Pays-Bas, , vol. 28, p. 396,398 Chem. Zentralbl., , vol. 81, # I p. 260 |
|
~%
6376-14-3 |
| 文献：Chem. Zentralbl., , vol. 81, # I p. 260 Recueil des Travaux Chimiques des Pays-Bas, , vol. 28, p. 395 |
| 海关编码 | 2922299090 |
|---|---|
| 中文概述 | 2922299090. 其他氨基(萘酚、酚)及醚、酯〔包括它们的盐, 但含有一种以上含氧基的除外〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0% |
| 申报要素 | 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装 |
| Summary | 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
